FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term glycerophospholipid phospholipase A1 activity ID (Ontology) GO:0008970 (Gene Ontology)
Definition Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospholipid + H2O = a 2-acyl-sn-glycero-3-phospholipid + a fatty acid + H+. Note that the substrate has a diacyl group attached to the glycerol group.
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Gene Groups Genes
 glycerophospholipid phospholipase A1 activity (all annotations which use CV term, excluding "NOT" statements)       1      1
     enables | glycerophospholipid phospholipase A1 activity       --       1
Spanning Tree (Parents/Children)
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glycerophospholipase activity________
carboxylic ester hydrolase activity__|
                                     A1-type glycerophospholipase activity
                                      |__glycerophospholipid phospholipase A1 activity  2 rec.
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Is a A1-type glycerophospholipase activity
Part of
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Synonyms
  • "diacylphospholipase A1 activity" BROAD
    "phosphatidylcholine 1-acylhydrolase activity" NARROW
    "phosphatidylserine 1-acylhydrolase activity" NARROW
    "phospholipase A1 activity" RELATED
Secondary IDs
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EC:3.1.1.32
MetaCyc:PHOSPHOLIPASE-A1-RXN
Reactome:R-HSA-1482827 "PC is hydrolyzed to 2-acyl LPC by PLA2G4C"
Reactome:R-HSA-1482828 "PE is hydrolyzed to 2-acyl LPE by PLA2[4]"
Reactome:R-HSA-1482847 "PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM)"
Reactome:R-HSA-1482862 "PC is hydrolysed to 2-acyl LPC by PLA2[7]"
Reactome:R-HSA-1482892 "PE is hydrolyzed to 2-acyl LPE by PLA2G4C"
Reactome:R-HSA-1482920 "PG is hydrolyzed to 2-acyl LPG by PLA2[14]"
Reactome:R-HSA-1482932 "PI is hydrolyzed to 2-acyl LPI by PLA2[13]"
Reactome:R-HSA-5694485 "ABHD3 hydrolyses LPC(14:0) to 1AGPC"
RHEA:67424