FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

dosage compensation by hyperactivation of X chromosome

ID (Ontology)

GO:0009047 (Gene Ontology)

Definition

Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global hyperactivation of all, or most of, the genes on the X-chromosome in the heterogametic sex, leading to a two-fold increase in gene expression from this chromosome. An example of this is found in Drosophila melanogaster.[ PubMed:11498577 PubMed:1568251 ]

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
dosage compensation by hyperactivation of X chromosome (all annotations which use CV term, excluding "NOT" statements)
involved_in \| dosage compensation by hyperactivation of X chromosome

Spanning Tree (Parents/Children)

  epigenetic regulation of gene expression
   |__sex-chromosome dosage compensation
       |__dosage compensation by hyperactivation of X chromosome  25 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	sex-chromosome dosage compensation
Part of
Synonyms & Secondary IDs
Synonyms

Secondary IDs

External Crossreferences & Linkouts
	Wikipedia:XY_sex-determination_system