FB2026_03 , released September 17, 2026
CV Term Report
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Term 7-methylguanosine RNA capping ID (Ontology) GO:0009452 (Gene Ontology)
Definition The sequence of enzymatic reactions by which the RNA 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript. Additional methylation can occur on the ribose sugars of the first and second nucleotides adjacent to the m7G nRNA cap. These methylations are often referred to as N6,2'-O-dimethyladenosine (m6,2A) and N6,2'-O-dimethylguanosine (m6,2G), respectively.[ PubMed:9266685 ]
Also Known As"m(7)G RNA capping"
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 7-methylguanosine RNA capping (all annotations which use CV term, excluding "NOT" statements)
     involved_in | 7-methylguanosine RNA capping
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  RNA 5'-end processing
   |__RNA capping
       |__7-methylguanosine RNA capping  6 rec.
           |__7-methylguanosine mRNA capping 5 rec.
           |__RNA 5'-cap (guanine-N7)-methylation 1 rec.
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Synonyms
  • "m(7)G RNA capping" EXACT
    "RNA capping" BROAD
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