FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
Help Close All Open All
General Information
Term pseudouridine synthase activity ID (Ontology) GO:0009982 (Gene Ontology)
Definition Catalysis of the reaction: a uridine in RNA = a pseudouridine in RNA. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       9
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 pseudouridine synthase activity (all annotations which use CV term, excluding "NOT" statements)       2      9
     enables | pseudouridine synthase activity       --       9
Spanning Tree (Parents/Children)
Only view relationship: 
  isomerase activity
   |__intramolecular transferase activity
       |__pseudouridine synthase activity  11 rec.
           |__rRNA pseudouridine synthase activity
           |   |__16S rRNA pseudouridine(516) synthase activity
           |   |__21S rRNA pseudouridine(2819) synthase activity
           |   |__23S rRNA pseudouridine(746) synthase activity
           |   |__23S rRNA pseudouridine(955/2504/2580) synthase activity
           |   |__23S rRNA pseudouridine(1911/1915/1917) synthase activity
           |   |__23S rRNA pseudouridine(2457) synthase activity
           |   |__23S rRNA pseudouridine(2604) synthase activity
           |   |__23S rRNA pseudouridine(2605) synthase activity
           |__snRNA pseudouridine synthase activity
           |__tRNA pseudouridine synthase activity 6 rec.
               |__mitochondrial tRNA pseudouridine(27/28) synthase activity 1 rec.
               |__tRNA pseudouridine(13) synthase activity 1 rec.
               |__tRNA pseudouridine(31) synthase activity
               |__tRNA pseudouridine(32) synthase activity
               |__tRNA pseudouridine(38-40) synthase activity
               |__tRNA pseudouridine(38/39) synthase activity 1 rec.
               |__tRNA pseudouridine(55) synthase activity 1 rec.
               |__tRNA pseudouridine(65) synthase activity
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a intramolecular transferase activity
Part of
hide Synonyms & Secondary IDs
Synonyms
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-6782381 "PUS1 isoform 2 isomerizes uridine residues to pseudouridine residues in the anticodon stems of tRNAs"
Reactome:R-HSA-6786583 "PUS7 isomerizes uridine to pseudouridine in tRNAs"
Reactome:R-HSA-6787566 "PUS1 isoform 1 isomerizes uridine-27, uridine-28 to pseudouridine residues in tRNA(Lys,Ser)"
Reactome:R-HSA-6790905 "Box H/ACA snoRNP transforms uridine to pseudouridine in pre-rRNA"
Reactome:R-HSA-8870289 "PUS3 isomerizes uridine-39 to pseudouridine-39 in tRNA"
Reactome:R-HSA-9936243 "RPUSD4 in the mitochondrial pseudouridylation module transforms uridine-1397 to pseudouridine-1397 in mitochondrial 16S rRNA"
Reactome:R-HSA-9937369 "RPUSD3,TRUB2 pseudouridylates MT-CO1,MT-CO3 mRNA"
RHEA:48348
RHEA:56644