FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term acireductone dioxygenase [iron(II)-requiring] activity ID (Ontology) GO:0010309 (Gene Ontology)
Definition Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2 = 4-methylthio-2-oxobutanoate + formate + H+.[ EC:1 ]
Also Known As"1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase activity" ; "acireductone dioxygenase (Fe2+-requiring) activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 acireductone dioxygenase [iron(II)-requiring] activity (all annotations which use CV term, excluding "NOT" statements)
     enables | acireductone dioxygenase [iron(II)-requiring] activity
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oxidoreductase activity, acting on single donors with incorporation of molecular oxygen__
dioxygenase activity_____________________________________________________________________|
                                                                                         oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
                                                                                          |__acireductone dioxygenase [iron(II)-requiring] activity  1 rec.
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Is a oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
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Synonyms
  • "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase activity" EXACT
    "1,2-dihydroxy-5-(methylthio)pent-1-en-3-one:oxygen oxidoreductase (formate-forming)" RELATED[ EC:1 ]
    "2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase" BROAD
    "aci-reductone dioxygenase" BROAD
    "acireductone dioxygenase (Fe2+-requiring) activity" EXACT
    "acireductone dioxygenase activity" BROAD[ EC:1 ]
    "ARD'" RELATED
    "ARD1" RELATED
    "E-2'" RELATED
Secondary IDs
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EC:1.13.11.54
KEGG_REACTION:R07364
MetaCyc:R147-RXN
Reactome:R-HSA-1237119 "Acireductone is oxidized to MOB"
RHEA:24504