FB2026_03 , released September 17, 2026
CV Term Report
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Term regulation of pyruvate decarboxylation to acetyl-CoA ID (Ontology) GO:0010510 (Gene Ontology)
Definition Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate. In most organisms, this pathway links glycolysis to the TCA cycle, by a series of three reactions carried out by a multisubunit complex called the 'pyruvate dehydrogenase complex', even though pyruvate dehydrogenase activity describes only one of those reactions.
Also Known As"regulation of acetyl-CoA biosynthetic process from pyruvate"
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 regulation of pyruvate decarboxylation to acetyl-CoA (all annotations which use CV term, excluding "NOT" statements)
     involved_in | regulation of pyruvate decarboxylation to acetyl-CoA
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acetyl-CoA biosynthetic process
 |__pyruvate decarboxylation to acetyl-CoA______________________
pyruvate metabolic process                                      |
 |__pyruvate decarboxylation to acetyl-CoA______________________|
aerobic respiration                                             |
 |__pyruvate decarboxylation to acetyl-CoA______________________|
regulation of biosynthetic process                              |
 |__regulation of acyl-CoA biosynthetic process_________________|
regulation of fatty acid metabolic process                      |
 |__regulation of acyl-CoA biosynthetic process_________________|
regulation of nucleobase-containing compound metabolic process  |
 |__regulation of acyl-CoA biosynthetic process_________________|
regulation of sulfur metabolic process                          |
 |__regulation of acyl-CoA biosynthetic process_________________|
regulation of phosphorus metabolic process                      |
 |__regulation of acyl-CoA biosynthetic process_________________|
acyl-CoA biosynthetic process                                   |
 |__regulation of acyl-CoA biosynthetic process_________________|
                                                                regulation of pyruvate decarboxylation to acetyl-CoA  4 rec.
                                                                 |__negative regulation of pyruvate decarboxylation to acetyl-CoA 1 rec.
                                                                 |__positive regulation of pyruvate decarboxylation to acetyl-CoA 2 rec.
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Is a regulation of acyl-CoA biosynthetic process
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Synonyms
  • "regulation of acetyl-CoA biosynthetic process from pyruvate" EXACT
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Reactome:R-HSA-204174 "Regulation of pyruvate dehydrogenase (PDH) complex"