FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term coenzyme A diphosphatase activity ID (Ontology) GO:0010945 (Gene Ontology)
Definition Catalysis of the reaction: an acyl-coenzyme A or its derivatives + H2O = adenosine 3',5'-bisphosphate + an acyl-4'-phosphopantetheine + 2 H+. This reaction can also use coenzyme A as a substrate.[ PubMed:10922370 PubMed:16185196 ]
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       5
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 Gene Groups Genes
 coenzyme A diphosphatase activity (all annotations which use CV term, excluding "NOT" statements)       1      5
     enables | coenzyme A diphosphatase activity       --       5
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  hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
   |__pyrophosphatase activity
       |__coenzyme A diphosphatase activity  6 rec.
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Is a pyrophosphatase activity
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Synonyms
  • "CoA diphosphatase activity" RELATED
    "CoA pyrophosphatase activity" RELATED
    "coenzyme A pyrophosphatase activity" RELATED
Secondary IDs
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EC:3.6.1.77
MetaCyc:RXN-10811
Reactome:R-HSA-6809354 "NUDT7 hydrolyses CoA-SH to 3',5'-ADP and PPANT"
Reactome:R-HSA-6810474 "NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT"
Reactome:R-HSA-9837354 "NUDT8 hydrolyzes CoA-SH to PPANT"
RHEA:50044
RHEA:64988