FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity ID (Ontology) GO:0015018 (Gene Ontology)
Definition Catalysis of the reaction: 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + UDP-alpha-D-glucuronate = 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + H+ + UDP.[ EC:2 ]
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       3
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity (all annotations which use CV term, excluding "NOT" statements)       3
     enables | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity       3
Spanning Tree (Parents/Children)
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UDP-glycosyltransferase activity__
hexosyltransferase activity_______|
                                  glucuronosyltransferase activity
                                   |__galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity  3 rec.
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Is a glucuronosyltransferase activity
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Synonyms
  • "glucuronosyltransferase I activity" NARROW[ EC:2 ]
    "UDP-glucuronate:3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosyl-protein D-glucuronosyltransferase activity" RELATED[ EC:2 ]
    "UDPglucuronate:3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosyl-protein D-glucuronosyltransferase activity" RELATED[ EC:2 ]
    "uridine diphosphate glucuronic acid:acceptor glucuronosyltransferase activity" RELATED[ EC:2 ]
Secondary IDs
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EC:2.4.1.135
MetaCyc:2.4.1.135-RXN
Reactome:R-HSA-1889955 "B3GAT dimers transfer GlcA to tetrasaccharide linker"
Reactome:R-HSA-3560802 "Defective B3GAT3 does not transfer GlcA to tetrasaccharide linker"
Reactome:R-HSA-9638064 "B3GAT3 dimer transfers GlcA to tetrasaccharide linker"
RHEA:24168