FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term glucuronosyltransferase activity ID (Ontology) GO:0015020 (Gene Ontology)
Definition Catalysis of the reaction: glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + H+ + UDP.
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       6
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 glucuronosyltransferase activity (all annotations which use CV term, excluding "NOT" statements)       1      6
     enables | glucuronosyltransferase activity       --       6
Spanning Tree (Parents/Children)
Only view relationship: 
glycosyltransferase activity
 |__UDP-glycosyltransferase activity__
 |__hexosyltransferase activity_______|
                                      glucuronosyltransferase activity  13 rec.
                                       |__asioloorosomucoid beta-1,3-glucuronosyltransferase activity 2 rec.
                                       |__bilirubin-glucuronoside glucuronosyltransferase activity
                                       |__galactosyl beta-1,3 N-acetylgalactosamine beta-1,3-glucuronosyltransferase activity 2 rec.
                                       |__galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity 3 rec.
                                       |__glucuronoxylan glucuronosyltransferase activity
                                       |__luteolin 7-O-glucuronosyltransferase activity
                                       |__luteolin-7-O-diglucuronide 4'-O-glucuronosyltransferase activity
                                       |__luteolin-7-O-glucuronide 7-O-glucuronosyltransferase activity
                                       |__N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity 2 rec.
                                       |__N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity 3 rec.
                                       |__N-acetyllactosamine beta-1,3-glucuronosyltransferase activity 2 rec.
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Is a UDP-glycosyltransferase activity
hexosyltransferase activity
Part of
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Synonyms
  • "1-naphthol glucuronyltransferase activity" NARROW[ EC:2 ]
    "1-naphthol-UDP-glucuronosyltransferase activity" NARROW[ EC:2 ]
    "17-beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW[ EC:2 ]
    "17-OH steroid UDPGT activity" NARROW[ EC:2 ]
    "17beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW[ EC:2 ]
    "3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW[ EC:2 ]
    "3-OH androgenic UDPGT activity" NARROW[ EC:2 ]
    "3alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW[ EC:2 ]
    "4-hydroxybiphenyl UDP-glucuronosyltransferase activity" NARROW[ EC:2 ]
    "4-methylumbelliferone UDP-glucuronosyltransferase activity" NARROW[ EC:2 ]
    "4-nitrophenol UDP-glucuronyltransferase activity" NARROW[ EC:2 ]
    "4-nitrophenol UDPGT activity" NARROW[ EC:2 ]
    "bilirubin glucuronyltransferase activity" NARROW[ EC:2 ]
    "bilirubin monoglucuronide glucuronyltransferase activity" NARROW[ EC:2 ]
    "bilirubin UDP-glucuronosyltransferase activity" NARROW[ EC:2 ]
    "bilirubin UDPGT activity" NARROW[ EC:2 ]
    "bilirubin uridine diphosphoglucuronyltransferase activity" NARROW[ EC:2 ]
    "ciramadol UDP-glucuronyltransferase activity" NARROW[ EC:2 ]
    "estriol UDPglucuronosyltransferase activity" NARROW[ EC:2 ]
    "estrone UDPglucuronosyltransferase activity" NARROW[ EC:2 ]
    "GT activity" RELATED[ EC:2 ]
    "morphine glucuronyltransferase activity" NARROW[ EC:2 ]
    "p-hydroxybiphenyl UDP glucuronyltransferase activity" NARROW[ EC:2 ]
    "p-nitrophenol UDP-glucuronosyltransferase activity" NARROW[ EC:2 ]
    "p-nitrophenol UDP-glucuronyltransferase activity" NARROW[ EC:2 ]
    "p-nitrophenylglucuronosyltransferase activity" NARROW[ EC:2 ]
    "p-phenylphenol glucuronyltransferase activity" NARROW[ EC:2 ]
    "phenyl-UDP-glucuronosyltransferase activity" NARROW[ EC:2 ]
    "PNP-UDPGT" RELATED[ EC:2 ]
    "pnp-UDPGT activity" NARROW[ EC:2 ]
    "UDP glucuronate-estradiol-glucuronosyltransferase activity" NARROW[ EC:2 ]
    "UDP glucuronate-estriol glucuronosyltransferase activity" NARROW[ EC:2 ]
    "UDP glucuronic acid transferase activity" RELATED[ EC:2 ]
    "UDP glucuronosyltransferase activity" RELATED[ EC:2 ]
    "UDP glucuronyltransferase activity" RELATED[ EC:2 ]
    "UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)" RELATED[ EC:2 ]
    "UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW[ EC:2 ]
    "UDP-glucuronate-bilirubin glucuronyltransferase activity" NARROW[ EC:2 ]
    "UDP-glucuronosyltransferase activity" RELATED[ EC:2 ]
    "UDP-glucuronyltransferase activity" RELATED[ EC:2 ]
    "UDPGA transferase activity" RELATED[ EC:2 ]
    "UDPGA-glucuronyltransferase activity" RELATED[ EC:2 ]
    "UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity" NARROW[ EC:2 ]
    "UDPGT activity" RELATED[ EC:2 ]
    "uridine 5'-diphosphoglucuronyltransferase activity" RELATED[ EC:2 ]
    "uridine diphosphate glucuronyltransferase activity" RELATED[ EC:2 ]
    "uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity" NARROW[ EC:2 ]
    "uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW[ EC:2 ]
    "uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity" NARROW[ EC:2 ]
    "uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity" NARROW[ EC:2 ]
    "uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity" NARROW[ EC:2 ]
    "uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity" NARROW[ EC:2 ]
    "uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity" NARROW[ EC:2 ]
    "uridine diphosphoglucuronate-estriol glucuronosyltransferase activity" NARROW[ EC:2 ]
    "uridine diphosphoglucuronosyltransferase activity" RELATED[ EC:2 ]
    "uridine diphosphoglucuronyltransferase activity" RELATED[ EC:2 ]
Secondary IDs
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EC:2.4.1.17
MetaCyc:UDP-GLUCURONOSYLTRANSFERASE-RXN
Reactome:R-HSA-158546 "UGTs glucuronate APAP to APAP-GlcA"
Reactome:R-HSA-159179 "UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG"
Reactome:R-HSA-159194 "UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG"
Reactome:R-HSA-174916 "Formation of N-glucuronides"
Reactome:R-HSA-174931 "UGTs transfer GlcA from UDP-GlcA to O-centre substrates"
Reactome:R-HSA-2162099 "abacavir + UDP-glucuronate => abacavir 5'-glucuronide + UDP"
Reactome:R-HSA-5604954 "Defective UGT1A4 does not transfer GlcA from UDP-GlcA to BIL"
Reactome:R-HSA-5604975 "Defective UGT1A1 does not transfer GlcA from UDP-GlcA to BIL"
Reactome:R-HSA-5617143 "B4GAT1:LARGE transfers initial GlcA to matriglycan chain"
Reactome:R-HSA-8941701 "UGT1A10 transfers GlcA from UDP-GlcA to GCTN"
Reactome:R-HSA-9036102 "Defective UGT1A1 does not transfer GlcA from UDP-GlcA to BMG"
Reactome:R-HSA-9036104 "Defective UGT1A4 does not transfer GlcA from UDP-GlcA to BMG"
Reactome:R-HSA-9632038 "UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG"
Reactome:R-HSA-9632039 "UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG"
Reactome:R-HSA-9638097 "LARGE1,2 elongates matriglycan chain with GlcA"
Reactome:R-HSA-9749977 "UGT1A6 glucuronates ST"
Reactome:R-HSA-9756134 "UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL"
Reactome:R-HSA-9756156 "UGT1A3 lactonizes ATV to ATVL"
Reactome:R-HSA-9756183 "UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL"
Reactome:R-HSA-9758661 "UGT2B7,2B17,1A3 glucuronidates PRED metabolites"
RHEA:21032
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