FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term proton transmembrane transporter activity ID (Ontology) GO:0015078 (Gene Ontology)
Definition Enables the transfer of a proton from one side of a membrane to the other.
Also Known As "hydrogen ion transmembrane transporter activity" ; "proton transporter activity"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION      20
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 proton transmembrane transporter activity (all annotations which use CV term, excluding "NOT" statements)      20
     enables | proton transmembrane transporter activity      20
Spanning Tree (Parents/Children)
Only view relationship: 
  monoatomic ion transmembrane transporter activity
   |__monoatomic cation transmembrane transporter activity
       |__proton transmembrane transporter activity  127 rec.
           |__3-sulfino-L-alanine: proton, glutamate antiporter activity 1 rec.
           |__acetylcholine:proton antiporter activity
           |__acridine:proton antiporter activity
           |__azole:proton antiporter activity
           |   |__aminotriazole:proton antiporter activity
           |   |__fluconazole:proton antiporter activity
           |   |__L-histidine, sodium:proton antiporter activity
           |__benomyl:proton antiporter activity
           |__chloride:proton antiporter activity 3 rec.
           |__cycloheximide:proton antiporter activity
           |__cytochrome-c oxidase activity 7 rec.
           |__diphosphate hydrolysis-driven proton transmembrane transporter activity
           |__gamma-aminobutyric acid:proton antiporter activity 2 rec.
           |__glycine:proton antiporter activity
           |__L-alanine:proton antiporter activity
           |__L-glutamate:proton antiporter activity 1 rec.
           |   |__aspartate:glutamate, proton antiporter activity 1 rec.
           |__metal cation:proton antiporter activity 10 rec.
           |   |__calcium:proton antiporter activity 1 rec.
           |   |__lithium:proton antiporter activity
           |   |__manganese:proton antiporter activity
           |   |__potassium:proton antiporter activity 2 rec.
           |   |__sodium:proton antiporter activity(+) 7 rec.
           |   |__zinc:proton antiporter activity(+)
           |__monoamine:proton antiporter activity 1 rec.
           |__NADH dehydrogenase (ubiquinone) activity 24 rec.
           |__P-type proton-exporting transporter activity
           |   |__P-type potassium:proton transporter activity
           |__polyamine:proton antiporter activity
           |__polyspecific organic cation:proton antiporter activity
           |__proton channel activity 33 rec.
           |   |__proton-transporting ATP synthase activity, rotational mechanism 29 rec.
           |   |__voltage-gated proton channel activity
           |__proton-translocating NAD(P)+ transhydrogenase activity
           |__proton-transporting ATPase activity, rotational mechanism 37 rec.
           |__quinol-cytochrome-c reductase activity 8 rec.
           |__solute:proton symporter activity 2 rec.
           |   |__3-hydroxyphenyl propionate:proton symporter activity
           |   |__acetate:proton symporter activity
           |   |__allantoin:proton symporter activity
           |   |__alpha-glucoside:proton symporter activity
           |   |__alpha-ketoglutarate:proton symporter activity
           |   |__amino acid:proton symporter activity(+) 1 rec.
           |   |__aromatic amino acid:proton symporter activity(+)
           |   |__auxin:proton symporter activity
           |   |__carbohydrate:proton symporter activity(+)
           |   |__citrate:proton symporter activity
           |   |__cytosine:proton symporter activity
           |   |__ferric enterobactin:proton symporter activity
           |   |__ferric triacetylfusarinine C:proton symporter activity
           |   |__folic acid:proton symporter activity
           |   |__glucosinolate:proton symporter activity
           |   |__lactate:proton symporter activity 1 rec.
           |   |__malate:proton symporter activity
           |   |__myo-inositol:proton symporter activity
           |   |__nitrate:proton symporter activity
           |   |__nucleoside:proton symporter activity(+)
           |   |__peptide:proton symporter activity
           |   |__phosphate:proton symporter activity
           |   |__potassium:proton symporter activity
           |   |__quaternary ammonium group:proton symporter activity(+)
           |   |__selenite:proton symporter activity
           |   |__shikimate:proton symporter activity
           |   |__sialic acid:proton symporter activity
           |   |__succinate:proton symporter activity
           |   |__sulfate:proton symporter activity(+)
           |   |__thiamine:proton symporter activity(+)
           |__tetracycline:proton antiporter activity
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Is a monoatomic cation transmembrane transporter activity
Part of
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Synonyms
  • "hydrogen ion transmembrane transporter activity" EXACT
    "proton transporter activity" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-1222516 "Intraphagosomal pH is lowered to 5 by V-ATPase"
Reactome:R-HSA-164834 "Enzyme-bound ATP is released"
Reactome:R-HSA-168313 "Virion-associated M2 protein mediated ion infusion"
Reactome:R-HSA-170026 "UCP1 imports a proton"
Reactome:R-HSA-74723 "Endosome acidification"
Reactome:R-HSA-917841 "Acidification of Tf:TfR1 containing endosome"
Reactome:R-HSA-9864415 "AAC1 imports a proton"