FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

ferrous iron transmembrane transporter activity

ID (Ontology)

GO:0015093 (Gene Ontology)

Definition

Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other.[ ISBN:0198506732 ]

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
ferrous iron transmembrane transporter activity (all annotations which use CV term, excluding "NOT" statements)
enables \| ferrous iron transmembrane transporter activity

Spanning Tree (Parents/Children)

  transition metal ion transmembrane transporter activity
   |__iron ion transmembrane transporter activity
       |__ferrous iron transmembrane transporter activity  1 rec.
           |__high-affinity ferrous iron transmembrane transporter activity

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	iron ion transmembrane transporter activity
Part of
Synonyms & Secondary IDs
Synonyms
	"ferrous iron uptake transmembrane transporter activity" RELATED
Secondary IDs

External Crossreferences & Linkouts
	MetaCyc:TRANS-RXN-8 Reactome:R-HSA-1362417 "Mitoferrin translocates iron from the mitochondrial intermembrane space to the mitochondrial matrix" Reactome:R-HSA-442368 "SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region" Reactome:R-HSA-5655760 "Defective SLC40A1 does not transport Fe3+ from extracellular region to cytosol" Reactome:R-HSA-9911596 "FeoAB transports Fe2+ from periplasmic space to the cytosol" Reactome:R-HSA-9911598 "EfeUOB transport Fe2+ from periplasmic space to the cytosol"