FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term chloride transmembrane transporter activity ID (Ontology) GO:0015108 (Gene Ontology)
Definition Enables the transfer of chloride ions from one side of a membrane to the other.
Also Known As"chloride ion transmembrane transporter activity"
Comment
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 Genes
 chloride transmembrane transporter activity (all annotations which use CV term, excluding "NOT" statements)
     enables | chloride transmembrane transporter activity
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  monoatomic ion transmembrane transporter activity
   |__monoatomic anion transmembrane transporter activity
       |__chloride transmembrane transporter activity  54 rec.
           |__chloride channel activity 38 rec.
           |   |__extracellularly glutamate-gated chloride channel activity 2 rec.
           |   |__extracellularly glycine-gated chloride channel activity
           |   |__GABA-gated chloride ion channel activity 4 rec.
           |   |__glycine-gated chloride ion channel activity 3 rec.
           |   |__histamine-gated chloride channel activity 3 rec.
           |   |__intracellularly ATP-gated chloride channel activity
           |   |__intracellularly calcium-gated chloride channel activity 8 rec.
           |   |__pH-gated chloride channel activity 6 rec.
           |   |__serotonin-gated chloride channel activity
           |   |__voltage-gated chloride channel activity(+) 3 rec.
           |   |__volume-sensitive chloride channel activity 3 rec.
           |__chloride:bicarbonate antiporter activity 1 rec.
           |   |__sodium,bicarbonate:chloride antiporter activity
           |__chloride:monoatomic cation symporter activity 11 rec.
           |   |__potassium:chloride symporter activity(+) 6 rec.
           |   |__sodium:chloride symporter activity(+) 8 rec.
           |__chloride:proton antiporter activity 3 rec.
           |__oxalate:chloride antiporter activity
           |__sulfate:chloride antiporter activity
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Is a monoatomic anion transmembrane transporter activity
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Synonyms
  • "ATP-dependent chloride transmembrane transporter activity" NARROW
    "ATPase-coupled chloride transmembrane transporter activity" NARROW
    "chloride ABC transporter" NARROW
    "chloride ion transmembrane transporter activity" EXACT
    "chloride transporting ATPase activity" NARROW
    "chloride-transporting ATPase activity" NARROW
Secondary IDs
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Reactome:R-HSA-5678822 "Defective CFTR does not transport Cl- from cytosol to extracellular region"
Reactome:R-HSA-5678863 "CFTR transports Cl- from cytosol to extracellular region"
Reactome:R-HSA-5678992 "Ivacaftor:CFTR G551D transports Cl- from cytosol to extracellular region"