FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term alpha-ketoglutarate transmembrane transporter activity ID (Ontology) GO:0015139 (Gene Ontology)
Definition Enables the transfer of alpha-ketoglutarate from one side of a membrane to the other. Alpha-ketoglutarate (or oxoglutarate) is a compound with important roles in carbohydrate and amino acid metabolism, especially in transamination reactions and as a component of the TCA cycle.[ ISBN:0198547684 ]
Also Known As"2-oxoglutarate transporter activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 alpha-ketoglutarate transmembrane transporter activity (all annotations which use CV term, excluding "NOT" statements)
     enables | alpha-ketoglutarate transmembrane transporter activity
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  carboxylic acid transmembrane transporter activity
   |__dicarboxylic acid transmembrane transporter activity
       |__alpha-ketoglutarate transmembrane transporter activity  2 rec.
           |__alpha-ketoglutarate:proton symporter activity
           |__citrate:2-oxoglutarate antiporter activity
           |__oxoglutarate:malate antiporter activity
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Is a dicarboxylic acid transmembrane transporter activity
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Synonyms
  • "2-oxoglutarate transporter activity" EXACT
Secondary IDs
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Reactome:R-HSA-372480 "2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix]"