FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term amino acid transmembrane transporter activity ID (Ontology) GO:0015171 (Gene Ontology)
Definition Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group.[ ISBN:0815340729 ]
Also Known As "amino acid permease activity"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION      26
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 amino acid transmembrane transporter activity (all annotations which use CV term, excluding "NOT" statements)       7     26
     enables | amino acid transmembrane transporter activity       --      26
Spanning Tree (Parents/Children)
Only view relationship: 
  transporter activity
   |__transmembrane transporter activity
       |__amino acid transmembrane transporter activity  96 rec.
           |__5-aminolevulinic acid transmembrane transporter activity
           |__ABC-type amino acid transporter activity
           |   |__ABC-type D-methionine transporter activity
           |   |__ABC-type L-cysteine transporter activity
           |   |__ATPase-coupled nonpolar-amino acid transporter activity
           |   |__ATPase-coupled polar amino acid-transporter activity(+)
           |__acidic amino acid transmembrane transporter activity 9 rec.
           |   |__L-aspartate transmembrane transporter activity(+) 6 rec.
           |   |__L-glutamate transmembrane transporter activity(+) 8 rec.
           |__amino acid:monoatomic cation antiporter activity 3 rec.
           |   |__3-sulfino-L-alanine: proton, glutamate antiporter activity 1 rec.
           |   |__gamma-aminobutyric acid:proton antiporter activity 2 rec.
           |   |__glycine:proton antiporter activity
           |   |__L-alanine:proton antiporter activity
           |   |__L-asparagine, sodium:proton antiporter activity
           |   |__L-glutamate:proton antiporter activity(+) 1 rec.
           |   |__L-glutamine, sodium:proton antiporter activity
           |   |__L-histidine, sodium:proton antiporter activity
           |__amino acid:monoatomic cation symporter activity 25 rec.
           |   |__amino acid:potassium symporter activity
           |   |__amino acid:proton symporter activity(+) 1 rec.
           |   |__amino acid:sodium symporter activity(+) 24 rec.
           |__arginine:agmatine antiporter activity
           |__arginine:ornithine antiporter activity
           |__basic amino acid transmembrane transporter activity 6 rec.
           |   |__broad specificity neutral L-amino acid:basic L-amino acid antiporter activity
           |   |__high-affinity basic amino acid transmembrane transporter activity(+) 2 rec.
           |   |__L-arginine transmembrane transporter activity(+) 5 rec.
           |   |__L-histidine transmembrane transporter activity(+) 1 rec.
           |   |__L-lysine transmembrane transporter activity(+) 5 rec.
           |   |__low-affinity basic amino acid transmembrane transporter activity(+)
           |__D-amino acid transmembrane transporter activity 1 rec.
           |   |__ABC-type D-methionine transporter activity
           |   |__D-alanine transmembrane transporter activity
           |   |__D-aspartate transmembrane transporter activity
           |   |__D-serine transmembrane transporter activity
           |__gamma-aminobutyric acid transmembrane transporter activity 5 rec.
           |   |__gamma-aminobutyric acid:proton antiporter activity 2 rec.
           |   |__gamma-aminobutyric acid:proton symporter activity 1 rec.
           |   |__gamma-aminobutyric acid:sodium:chloride symporter activity 1 rec.
           |   |__glutamate:gamma-aminobutyric acid antiporter activity
           |__glutamate-gated receptor activity 16 rec.
           |   |__AMPA glutamate receptor activity
           |   |__glutamate-gated calcium ion channel activity 7 rec.
           |   |__kainate selective glutamate receptor activity 9 rec.
           |   |__NMDA glutamate receptor activity 3 rec.
           |__L-amino acid transmembrane transporter activity 51 rec.
           |   |__3-sulfino-L-alanine: proton, glutamate antiporter activity 1 rec.
           |   |__L-alanine transmembrane transporter activity(+)
           |   |__L-amino acid efflux transmembrane transporter activity(+)
           |   |__L-arginine transmembrane transporter activity(+) 5 rec.
           |   |__L-asparagine transmembrane transporter activity(+)
           |   |__L-aspartate transmembrane transporter activity(+) 6 rec.
           |   |__L-cysteine transmembrane transporter activity(+)
           |   |__L-cystine transmembrane transporter activity 1 rec.
           |   |__L-diaminopimelate transmembrane transporter activity
           |   |__L-glutamate transmembrane transporter activity(+) 8 rec.
           |   |__L-glutamine transmembrane transporter activity(+)
           |   |__L-histidine transmembrane transporter activity(+) 1 rec.
           |   |__L-homoserine transmembrane transporter activity
           |   |__L-hydroxyproline transmembrane transporter activity
           |   |__L-isoleucine transmembrane transporter activity
           |   |__L-kynurenine transmembrane transporter activity
           |   |__L-leucine transmembrane transporter activity
           |   |__L-lysine transmembrane transporter activity(+) 5 rec.
           |   |__L-methionine transmembrane transporter activity(+)
           |   |__L-ornithine transmembrane transporter activity(+) 4 rec.
           |   |__L-phenylalanine transmembrane transporter activity
           |   |__L-proline transmembrane transporter activity 1 rec.
           |   |__L-serine transmembrane transporter activity 3 rec.
           |   |__L-threonine transmembrane transporter activity(+)
           |   |__L-tryptophan transmembrane transporter activity(+) 1 rec.
           |   |__L-tyrosine transmembrane transporter activity(+)
           |   |__L-valine transmembrane transporter activity
           |   |__N(6),N(6),N(6)-trimethyl-L-lysine transmembrane transporter activity
           |   |__S-adenosyl-L-methionine:S-adenosyl-L-homocysteine antiporter activity
           |__lysine:cadaverine antiporter activity
           |__methionine transmembrane transporter activity
           |   |__ABC-type D-methionine transporter activity
           |   |__L-methionine transmembrane transporter activity(+)
           |__neutral L-amino acid transmembrane transporter activity 16 rec.
               |__3-sulfino-L-alanine: proton, glutamate antiporter activity 1 rec.
               |__alanine transmembrane transporter activity(+)
               |__beta-alanine transmembrane transporter activity 1 rec.
               |__broad specificity neutral L-amino acid:basic L-amino acid antiporter activity
               |__glycine transmembrane transporter activity(+) 10 rec.
               |__L-asparagine transmembrane transporter activity(+)
               |__L-cysteine transmembrane transporter activity(+)
               |__L-glutamine transmembrane transporter activity(+)
               |__L-homoserine transmembrane transporter activity
               |__L-isoleucine transmembrane transporter activity
               |__L-leucine transmembrane transporter activity
               |__L-proline transmembrane transporter activity 1 rec.
               |__L-threonine transmembrane transporter activity(+)
               |__L-valine transmembrane transporter activity
               |__neutral L-amino acid secondary active transmembrane transporter activity(+)
               |__neutral L-amino acid:sodium symporter activity(+) 8 rec.
               |__neutral L-amino acid:sodium:chloride symporter activity
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Is a transmembrane transporter activity
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Synonyms
  • "amino acid permease activity" EXACT
    "amino acid transporter activity" BROAD
    "amino acid/choline transmembrane transporter activity" NARROW
    "general amino acid permease activity" RELATED
    "hydroxy/aromatic amino acid permease activity" RELATED
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-210439 "glutamate uptake by astrocytes"
Reactome:R-HSA-212642 "L-Glutamine transport into neurons"
Reactome:R-HSA-351987 "SLC6A6-mediated uptake of taurine and beta-alanine"
Reactome:R-HSA-352029 "SLC6A12 (BGT-1)-mediated uptake of GABA and betaine"
Reactome:R-HSA-352052 "SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol"
Reactome:R-HSA-352059 "SLC6A15-mediated amino acid uptake"
Reactome:R-HSA-352103 "SLC43A1 (LAT3)-mediated uptake of large neutral amino acids"
Reactome:R-HSA-352107 "SLC43A2 (LAT4)-mediated uptake of large neutral amino acids"
Reactome:R-HSA-352108 "SLC38A2 (ATA2)-mediated uptake of neutral amino acids"
Reactome:R-HSA-352119 "SLC38A1 (ATA1)-mediated uptake of neutral amino acids"
Reactome:R-HSA-352136 "SLC38A4 (ATA3)-mediated uptake of arginine and lysine"
Reactome:R-HSA-352158 "SLC16A10-mediated uptake of aromatic amino acids"
Reactome:R-HSA-352174 "SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine"
Reactome:R-HSA-352182 "SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine"
Reactome:R-HSA-352191 "SLC7A8-mediated uptake of neutral amino acids"
Reactome:R-HSA-352347 "SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine"
Reactome:R-HSA-352354 "SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine"
Reactome:R-HSA-352364 "SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine"
Reactome:R-HSA-352371 "SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine"
Reactome:R-HSA-352379 "SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane"
Reactome:R-HSA-352385 "SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane"
Reactome:R-HSA-375405 "SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol"
Reactome:R-HSA-375417 "SLC36A1-mediated uptake of glycine, proline, and alanine"
Reactome:R-HSA-375473 "SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol"
Reactome:R-HSA-375487 "SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol"
Reactome:R-HSA-375768 "SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids"
Reactome:R-HSA-375770 "SLC7A3 (CAT-3)-mediated uptake of cationic amino acids"
Reactome:R-HSA-375776 "SLC7A1 (CAT-1)-mediated uptake of cationic amino acids"
Reactome:R-HSA-375790 "SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids"
Reactome:R-HSA-376200 "SLC7A10-mediated uptake of small neutral amino acids"
Reactome:R-HSA-378513 "SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate"
Reactome:R-HSA-379415 "SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane"
Reactome:R-HSA-379426 "SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine"
Reactome:R-HSA-379432 "SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu"
Reactome:R-HSA-5653850 "Defective SLC36A2 does not cotransport Gly, L-Pro with H+ from extracellular region to cytosol"
Reactome:R-HSA-5655702 "Defective SLC3A1 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu"
Reactome:R-HSA-5659674 "Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol"
Reactome:R-HSA-5659734 "Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol"
Reactome:R-HSA-5660694 "Variant SLC6A20 does not cotransport L-Pro, Na+ from extracellulare region to cytosol"
Reactome:R-HSA-5660890 "Defective SLC7A9 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu"
Reactome:R-HSA-5660910 "Defective SLC7A7 does not exchange L-Arg for L-Leu, Na+ across the plasma membrane"
Reactome:R-HSA-888592 "Loading of GABA into clathrin sculpted GABA transport vesicle lumen"
Reactome:R-HSA-8952726 "SLC38A9 transports L-Arg from lysosomal lumen to cytosol"