FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term basic amino acid transmembrane transporter activity ID (Ontology) GO:0015174 (Gene Ontology)
Definition Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have side chains with a positive charge at pH 7.3.[ ISBN:0815340729 ]
Also Known As"basic amino acid permease activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_CELLULAR_COMPONENT
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 Genes
 basic amino acid transmembrane transporter activity (all annotations which use CV term, excluding "NOT" statements)
     enables | basic amino acid transmembrane transporter activity
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  transmembrane transporter activity
   |__amino acid transmembrane transporter activity
       |__basic amino acid transmembrane transporter activity  6 rec.
           |__broad specificity neutral L-amino acid:basic L-amino acid antiporter activity
           |__high-affinity basic amino acid transmembrane transporter activity 2 rec.
           |   |__high-affinity glutamine transmembrane transporter activity
           |   |__high-affinity L-arginine transmembrane transporter activity 2 rec.
           |   |__high-affinity L-histidine transmembrane transporter activity
           |   |__high-affinity lysine transmembrane transporter activity 2 rec.
           |__L-arginine transmembrane transporter activity 5 rec.
           |   |__high-affinity L-arginine transmembrane transporter activity 2 rec.
           |   |__L-lysine:L-arginine antiporter activity
           |   |__low-affinity L-arginine transmembrane transporter activity
           |__L-histidine transmembrane transporter activity 1 rec.
           |   |__high-affinity L-histidine transmembrane transporter activity
           |   |__L-histidine, sodium:proton antiporter activity
           |   |__L-histidine:histamine antiporter activity
           |__L-lysine transmembrane transporter activity 5 rec.
           |   |__high-affinity lysine transmembrane transporter activity 2 rec.
           |   |__L-lysine efflux transmembrane transporter activity
           |   |__L-lysine:L-arginine antiporter activity
           |__low-affinity basic amino acid transmembrane transporter activity
               |__low-affinity L-arginine transmembrane transporter activity
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Is a amino acid transmembrane transporter activity
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Synonyms
  • "basic amino acid permease activity" EXACT
    "basic amino acid transporter activity" BROAD
    "cationic amino acid transmembrane transporter activity" RELATED
Secondary IDs
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Reactome:R-HSA-8932851 "PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol"
Reactome:R-HSA-8959781 "SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix"