FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

choline transmembrane transporter activity

ID (Ontology)

GO:0015220 (Gene Ontology)

Definition

Enables the transfer of choline from one side of a membrane to the other. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.

Also Known As

"choline permease activity"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Gene Groups	Genes
choline transmembrane transporter activity (all annotations which use CV term, excluding "NOT" statements)
enables \| choline transmembrane transporter activity	--

Spanning Tree (Parents/Children)

  transporter activity
   |__transmembrane transporter activity
       |__choline transmembrane transporter activity  3 rec.
           |__ABC-type choline transporter activity
           |__choline:sodium symporter activity 1 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	transmembrane transporter activity
Part of
Synonyms & Secondary IDs
Synonyms
	"amino acid/choline transmembrane transporter activity" NARROW "choline permease activity" EXACT
Secondary IDs

External Crossreferences & Linkouts
	Reactome:R-HSA-429594 "SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol" Reactome:R-HSA-444433 "Cho transports from the extracellular space to the cytosol" Reactome:R-HSA-5658483 "Defective SLC5A7 does not cotransport Cho, Cl-, Na+ from extracellular region to cytosol" Reactome:R-HSA-6797956 "SLC44A1 transports Cho from cytosol to mitochondrial matrix"