FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term channel activity ID (Ontology) GO:0015267 (Gene Ontology)
Definition Enables the energy-independent facilitated diffusion of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.[ ISBN:0815340729 ]
Also Known As "channel/pore class transporter activity" ; "nonselective channel activity"
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION      11
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 channel activity (all annotations which use CV term, excluding "NOT" statements)       1     11
     enables | channel activity       --      11
Spanning Tree (Parents/Children)
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  transmembrane transporter activity
   |__passive transmembrane transporter activity
       |__channel activity  513 rec.
           |__ammonium channel activity 3 rec.
           |__bicarbonate channel activity
           |__borate channel activity
           |__channel-forming ionophore activity
           |__gated channel activity 361 rec.
           |   |__G-protein gated monoatomic ion channel activity(+)
           |   |__ligand-gated channel activity(+) 312 rec.
           |   |__mechanosensitive monoatomic ion channel activity(+) 18 rec.
           |   |__osmolarity-sensing monoatomic cation channel activity
           |   |__temperature-gated ion channel activity(+) 1 rec.
           |   |__voltage-gated channel activity(+) 43 rec.
           |__glycerol channel activity
           |__hydrogen peroxide channel activity
           |__methylammonium channel activity
           |__monoatomic ion channel activity 469 rec.
           |   |__ligand-gated monoatomic ion channel activity(+) 297 rec.
           |   |__light-activated monoatomic ion channel activity(+)
           |   |__mechanosensitive monoatomic ion channel activity(+) 18 rec.
           |   |__monoatomic anion channel activity(+) 44 rec.
           |   |__monoatomic cation channel activity(+) 230 rec.
           |   |__temperature-gated ion channel activity(+) 1 rec.
           |   |__voltage-gated monoatomic ion channel activity(+) 42 rec.
           |__narrow pore channel activity 14 rec.
           |   |__leak channel activity(+) 14 rec.
           |   |__narrow pore, gated channel activity
           |__urea channel activity
           |__water channel activity 11 rec.
           |__wide pore channel activity 12 rec.
               |__gap junction channel activity(+) 9 rec.
               |__gap junction hemi-channel activity 1 rec.
               |__porin activity(+) 3 rec.
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Is a passive transmembrane transporter activity
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Synonyms
  • "alpha-type channel activity" RELATED
    "channel-forming toxin activity" RELATED
    "channel/pore class transporter activity" EXACT
    "nonselective channel activity" EXACT
    "pore activity" BROAD
    "pore class transporter activity" RELATED
    "substrate-specific channel activity" RELATED
Secondary IDs
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Reactome:R-HSA-3779381 "H2O2 diffuses from the mitochondrial matrix to the cytosol"
Reactome:R-HSA-8953430 "PXMP2 trimer transports glycolate from cytosol to peroxisomal matrix"
Reactome:R-HSA-9857649 "p-S373-GJA1:p-S-ITGA5:ITGB1 (p-S373-Connexin-43:p-S-Integrin alpha5:Integrin beta1) transports ATP from the cytosol to the extracellular region"
Reactome:R-HSA-9857682 "p-S373-GJA1:p-S-ITGA5:ITGB1 (p-S373-Connexin-43:p-S-Integrin alpha5:Integrin beta1) transports prostaglandin E2 (PGE2) from the cytosol to the extracellular region"
Reactome:R-HSA-9905999 "Pannexin1 (PANX1) channel in a complex with P2RX7 transports ATP from the cytosol to the extracellular region"
TC:1