FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term intracellularly gated calcium channel activity ID (Ontology) GO:0015278 (Gene Ontology)
Definition Enables the transmembrane transfer of a calcium ion by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts.
Also Known As"calcium-release channel activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 intracellularly gated calcium channel activity (all annotations which use CV term, excluding "NOT" statements)
     enables | intracellularly gated calcium channel activity       --
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calcium channel activity
 |__ligand-gated calcium channel activity_________________________
ligand-gated monoatomic ion channel activity                      |
 |__intracellularly ligand-gated monoatomic ion channel activity__|
ligand-gated monoatomic cation channel activity                   |
 |__ligand-gated calcium channel activity_________________________|
                                                                  intracellularly gated calcium channel activity  7 rec.
                                                                   |__cADPR-sensitive calcium-release channel activity
                                                                   |__calcium-induced calcium release activity 1 rec.
                                                                   |   |__ryanodine-sensitive calcium-release channel activity 1 rec.
                                                                   |__inositol 1,4,5-trisphosphate-gated calcium channel activity 1 rec.
                                                                   |   |__inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels
                                                                   |__intracellularly ATP-gated calcium channel activity
                                                                   |__NAADP-sensitive calcium-release channel activity 2 rec.
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Is a intracellularly ligand-gated monoatomic ion channel activity
ligand-gated calcium channel activity
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Synonyms
  • "calcium-release channel activity" EXACT
    "intracellular ligand-gated calcium channel activity" RELATED
Secondary IDs
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Reactome:R-HSA-9717215 "ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol"