FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term potassium:chloride symporter activity ID (Ontology) GO:0015379 (Gene Ontology)
Definition Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + Cl-(out) = K+(in) + Cl-(in).
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 potassium:chloride symporter activity (all annotations which use CV term, excluding "NOT" statements)
     enables | potassium:chloride symporter activity
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chloride transmembrane transporter activity
 |__chloride:monoatomic cation symporter activity______
monoatomic anion:monoatomic cation symporter activity  |
 |__chloride:monoatomic cation symporter activity______|
metal ion transmembrane transporter activity           |
 |__potassium ion transmembrane transporter activity___|
                                                       potassium:chloride symporter activity  6 rec.
                                                        |__sodium:potassium:chloride symporter activity 3 rec.
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Is a potassium ion transmembrane transporter activity
chloride:monoatomic cation symporter activity
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Synonyms
  • "potassium ion symporter activity" BROAD
Secondary IDs
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Reactome:R-HSA-426155 "SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region"
Reactome:R-HSA-5623806 "Defective SLC12A6 does not cotransport K+, Cl- from cytosol to extracellular region"
RHEA:72427
TC:2.A.30.1.5