FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term primary active transmembrane transporter activity ID (Ontology) GO:0015399 (Gene Ontology)
Definition Enables the transfer of a solute from one side of a membrane to the other, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is powered by a primary energy source. Primary energy sources known to be coupled to transport are chemical such as ATP hydrolysis, redox energy and photon energy.[ PubMed:31613498 ]
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 primary active transmembrane transporter activity (all annotations which use CV term, excluding "NOT" statements)
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  transmembrane transporter activity
   |__active transmembrane transporter activity
       |__primary active transmembrane transporter activity  172 rec.
           |__active monoatomic ion transmembrane transporter activity 89 rec.
           |   |__ATPase-coupled monoatomic cation transmembrane transporter activity(+) 51 rec.
           |   |__cytochrome-c oxidase activity 7 rec.
           |   |__diphosphate hydrolysis-driven proton transmembrane transporter activity
           |   |__light-driven active monoatomic ion transmembrane transporter activity
           |   |__NADH dehydrogenase (ubiquinone) activity 23 rec.
           |   |__proton-translocating NAD(P)+ transhydrogenase activity
           |   |__quinol-cytochrome-c reductase activity 8 rec.
           |__ATPase-coupled transmembrane transporter activity 119 rec.
           |   |__ABC-type transporter activity(+) 59 rec.
           |   |__ATPase-coupled 2-aminoethylphosphonate transporter activity
           |   |__ATPase-coupled antimonite transmembrane transporter activity
           |   |__ATPase-coupled arsenite transmembrane transporter activity
           |   |__ATPase-coupled carboxylic acid transmembrane transporter activity(+)
           |   |__ATPase-coupled ion transmembrane transporter activity(+) 37 rec.
           |   |__ATPase-coupled lipid transmembrane transporter activity(+) 1 rec.
           |   |__ATPase-coupled lipo-chitin oligosaccharide transmembrane transporter activity
           |   |__ATPase-coupled monoatomic cation transmembrane transporter activity(+) 51 rec.
           |   |__ATPase-coupled phosphate ion transmembrane transporter activity
           |   |__ATPase-coupled urea transmembrane transporter activity
           |   |__P-type transmembrane transporter activity(+) 18 rec.
           |   |__protein-transporting ATPase activity(+) 1 rec.
           |__decarboxylation-driven active transmembrane transporter activity
           |   |__glutaconyl-CoA decarboxylase activity
           |__methyl transfer-driven active transmembrane transporter activity
           |__oxidoreduction-driven active transmembrane transporter activity 49 rec.
               |__cytochrome bo3 ubiquinol oxidase activity
               |__cytochrome-c oxidase activity 7 rec.
               |__NADH dehydrogenase (ubiquinone) activity 23 rec.
               |__plastoquinol--plastocyanin reductase activity
               |__proton-translocating NAD(P)+ transhydrogenase activity
               |__quinol-cytochrome-c reductase activity 8 rec.
               |__transmembrane ascorbate ferrireductase activity 9 rec.
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Synonyms
  • "primary active transporter" RELATED
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EC:7.-.-.-
TC:3