FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term ABC-type heme transporter activity ID (Ontology) GO:0015439 (Gene Ontology)
Definition Catalysis of the reaction: ATP + H2O + heme(in) = ADP + phosphate + heme(out).
Also Known As "ATP-dependent heme transmembrane transporter activity" ; "haem-transporting ATPase activity" ; "heme-transporting ATPase activity"
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       3
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 ABC-type heme transporter activity (all annotations which use CV term, excluding "NOT" statements)       3
     enables | ABC-type heme transporter activity       3
Spanning Tree (Parents/Children)
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transmembrane transporter activity
 |__heme transmembrane transporter activity________
ATPase-coupled transmembrane transporter activity  |
 |__ABC-type transporter activity__________________|
                                                   ABC-type heme transporter activity  3 rec.
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Is a heme transmembrane transporter activity
ABC-type transporter activity
Part of
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Synonyms
  • "ATP-dependent heme transmembrane transporter activity" EXACT
    "ATPase-coupled heme transmembrane transporter activity" RELATED
    "ATPase-coupled heme transporter activity" RELATED
    "haem-transporting ATPase activity" EXACT
    "heme ABC transporter" NARROW
    "heme-transporting ATPase activity" EXACT
    "protoheme IX ABC transporter activity" RELATED
Secondary IDs
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EC:7.6.2.5
MetaCyc:3.6.3.41-RXN
Reactome:R-HSA-1369065 "ABCB6 transports porphyrin from cytosol to mitchondrial matrix"
Reactome:R-HSA-382560 "ABC7, mABC1 and mABC2 mediate heme transport"
Reactome:R-HSA-5683355 "Defective ABCB6 does not transport porphyrin from cytosol into mitochondria matrix"
Reactome:R-HSA-917979 "ABCG2 tetramer transports heme from cytosol to extracellular region"
RHEA:19261