FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term dystroglycan complex ID (Ontology) GO:0016011 (Gene Ontology)
Definition A protein complex that includes alpha- and beta-dystroglycan, which are alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin.[ PubMed:15117830 PubMed:16710609 ]
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Genes (FBgn)GO_CELLULAR_COMPONENT
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 dystroglycan complex (all annotations which use CV term, excluding "NOT" statements)
     part_of | dystroglycan complex
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plasma membrane
 |__plasma membrane protein complex_____________
glycoprotein complex                            |
 |__dystrophin-associated glycoprotein complex__|
membrane protein complex                        |
 |__plasma membrane protein complex_____________|
plasma membrane protein complex                 |
 |__dystrophin-associated glycoprotein complex__|
                                                dystroglycan complex  5 rec.
                                                 |__sarcoglycan complex 4 rec.
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Is a plasma membrane protein complex
Part of dystrophin-associated glycoprotein complex
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