FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term L-kynurenine:2-oxoglutarate transaminase activity ID (Ontology) GO:0016212 (Gene Ontology)
Definition Catalysis of the reaction: 2-oxoglutarate + L-kynurenine = H2O + kynurenate + L-glutamate. The product 4-(2-aminophenyl)-2,4-dioxobutanoate is converted into kynurenate by a spontaneous reaction. Also acts on 3-hydroxykynurenine to form xanthurenate.[ EC:2 ]
Also Known As"kynurenine-oxoglutarate aminotransferase activity" ; "kynurenine-oxoglutarate transaminase activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 L-kynurenine:2-oxoglutarate transaminase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | L-kynurenine:2-oxoglutarate transaminase activity
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  transferase activity, transferring nitrogenous groups
   |__transaminase activity
       |__L-kynurenine:2-oxoglutarate transaminase activity  2 rec.
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Is a transaminase activity
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Synonyms
  • "kynurenine 2-oxoglutarate transaminase activity" RELATED[ EC:2 ]
    "kynurenine aminotransferase activity" BROAD[ EC:2 ]
    "kynurenine transaminase (cyclizing)" RELATED[ EC:2 ]
    "kynurenine--oxoglutarate aminotransferase activity" RELATED[ EC:2 ]
    "kynurenine-oxoglutarate aminotransferase activity" EXACT
    "kynurenine-oxoglutarate transaminase activity" EXACT
    "L-kynurenine aminotransferase activity" RELATED[ EC:2 ]
    "L-kynurenine:2-oxoglutarate aminotransferase activity" RELATED[ EC:2 ]
Secondary IDs
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EC:2.6.1.7
MetaCyc:RXN-21858
MetaCyc:RXN-21859
Reactome:R-HSA-893583 "kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate"
Reactome:R-HSA-893596 "PXLP-KYAT1 dimer transaminates L-KYN to KYNA"
Reactome:R-HSA-901097 "PXLP-KYAT3 (CCBL2) dimer transaminates L-KYN to KYNA"
RHEA:65560
RHEA:65884