FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term iron-sulfur cluster assembly ID (Ontology) GO:0016226 (Gene Ontology)
Definition The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
Also Known As"iron-sulphur cluster assembly"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 iron-sulfur cluster assembly (all annotations which use CV term, excluding "NOT" statements)
     involved_in | iron-sulfur cluster assembly       --
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  cellular component assembly
   |__metallo-sulfur cluster assembly
       |__iron-sulfur cluster assembly  31 rec.
           |__[2Fe-2S] cluster assembly 10 rec.
           |   |__regulation of [2Fe-2S] cluster assembly(+)
           |__[4Fe-4S] cluster assembly 13 rec.
           |   |__regulation of [4Fe-4S] cluster assembly(+)
           |__iron incorporation into metallo-sulfur cluster
           |__iron-sulfur-molybdenum cofactor assembly
           |   |__regulation of iron-sulfur-molybdenum cofactor assembly(+)
           |__molybdenum incorporation into iron-sulfur cluster
           |__nitrogenase P cluster assembly
           |__regulation of iron-sulfur cluster assembly
               |__negative regulation of iron-sulfur cluster assembly(+)
               |__positive regulation of iron-sulfur cluster assembly(+)
               |__regulation of [2Fe-2S] cluster assembly(+)
               |__regulation of [4Fe-4S] cluster assembly(+)
               |__regulation of iron-sulfur-molybdenum cofactor assembly(+)
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Is a metallo-sulfur cluster assembly
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Synonyms
  • "iron-sulfur cluster biosynthesis" RELATED
    "iron-sulphur cluster assembly" EXACT
Secondary IDs
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Reactome:R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis"
Reactome:R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly"