FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term N-sulfoglucosamine sulfohydrolase activity ID (Ontology) GO:0016250 (Gene Ontology)
Definition Catalysis of the reaction: N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate.[ EC:3 ]
Also Known As"N-sulphoglucosamine sulphohydrolase activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 N-sulfoglucosamine sulfohydrolase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | N-sulfoglucosamine sulfohydrolase activity
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  hydrolase activity
   |__hydrolase activity, acting on sulfur-nitrogen bonds
       |__N-sulfoglucosamine sulfohydrolase activity  1 rec.
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Is a hydrolase activity, acting on sulfur-nitrogen bonds
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Synonyms
  • "2-desoxy-D-glucoside-2-sulphamate sulphohydrolase (sulphamate sulphohydrolase)" RELATED[ EC:3 ]
    "heparin sulfamidase activity" RELATED[ EC:3 ]
    "N-sulfo-D-glucosamine sulfohydrolase activity" RELATED[ EC:3 ]
    "N-sulphoglucosamine sulphohydrolase activity" EXACT
    "sulfoglucosamine sulfamidase activity" RELATED[ EC:3 ]
    "sulphamidase activity" RELATED[ EC:3 ]
Secondary IDs
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EC:3.10.1.1
MetaCyc:N-SULFOGLUCOSAMINE-SULFOHYDROLASE-RXN
Reactome:R-HSA-1678708 "SGSH hydrolyses Heparan sulfate chain(2)"
Reactome:R-HSA-2090043 "SGSH hydrolyses Heparan sulfate chain(7)"
Reactome:R-HSA-2263444 "Defective SGSH does not hydrolyse Heparan sulfate chain(7)"
Reactome:R-HSA-9036050 "Defective SGSH does not hydrolyse Heparan sulfate chain(2)"
RHEA:17881