FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term protein-arginine N-methyltransferase activity ID (Ontology) GO:0016274 (Gene Ontology)
Definition Catalysis of the reaction: S-adenosyl-L-methionine + (protein)-arginine = S-adenosyl-L-homocysteine + (protein)-N-methyl-arginine.[ PubMed:12351636 PubMed:31284549 ]
Also Known As "PRMT activity"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION      10
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 protein-arginine N-methyltransferase activity (all annotations which use CV term, excluding "NOT" statements)       1     10
     enables | protein-arginine N-methyltransferase activity       --      10
Spanning Tree (Parents/Children)
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methyltransferase activity
 |__protein methyltransferase activity_____________________
N-methyltransferase activity                               |
 |__arginine N-methyltransferase activity__________________|
S-adenosylmethionine-dependent methyltransferase activity  |
 |__arginine N-methyltransferase activity__________________|
catalytic activity, acting on a protein                    |
 |__protein methyltransferase activity_____________________|
                                                           protein-arginine N-methyltransferase activity  13 rec.
                                                            |__histone H2AR3 methyltransferase activity
                                                            |__histone H3R2 methyltransferase activity 2 rec.
                                                            |__histone H3R8 methyltransferase activity
                                                            |__histone H3R17 methyltransferase activity 2 rec.
                                                            |__histone H3R26 methyltransferase activity
                                                            |__histone H4R3 methyltransferase activity 1 rec.
                                                            |__protein arginine N5-methyltransferase activity
                                                            |__protein-arginine omega-N asymmetric methyltransferase activity 6 rec.
                                                            |__protein-arginine omega-N monomethyltransferase activity 7 rec.
                                                            |__protein-arginine omega-N symmetric methyltransferase activity 3 rec.
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Is a protein methyltransferase activity
arginine N-methyltransferase activity
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Synonyms
  • "PRMT activity" EXACT
Secondary IDs
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Reactome:R-HSA-191790 "Loading and methylation of Sm proteins onto SMN Complexes"
Reactome:R-HSA-5205798 "PRMT1,PRMT6 methylate arginine-4 of histone H4"
Reactome:R-HSA-5205820 "PRMT6 methylates arginine-4 of histone H2A (H2AR3)"
Reactome:R-HSA-5205822 "CARM1 methylates arginine-18 (H3R17) of histone H3"
Reactome:R-HSA-5205824 "CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2)"
Reactome:R-HSA-5205867 "PRMT1 methylates arginine-12 of histone H2A (H2AR11)"
Reactome:R-HSA-5218952 "PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2)"
Reactome:R-HSA-5229010 "CARM1 methylates arginine-27 of histone H3 (H3R26)"
Reactome:R-HSA-5229203 "PRMT6 methylates histone H2A arginine-30 (H2AR29)"
Reactome:R-HSA-5661126 "PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4"
Reactome:R-HSA-8879123 "PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2"
Reactome:R-HSA-8934735 "PRMT1 arginine-methylates RUNX1"