FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term 1-phosphatidylinositol-5-phosphate 4-kinase activity ID (Ontology) GO:0016309 (Gene Ontology)
Definition Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 5-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ADP + H+.[ EC:2 ]
Also Known As "PIP4K"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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Relevant FlyBase reports
 Genes
 1-phosphatidylinositol-5-phosphate 4-kinase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | 1-phosphatidylinositol-5-phosphate 4-kinase activity       1
Spanning Tree (Parents/Children)
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lipid kinase activity___________________________________
phosphotransferase activity, alcohol group as acceptor__|
                                                        phosphatidylinositol kinase activity
                                                         |__1-phosphatidylinositol-5-phosphate 4-kinase activity  1 rec.
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Is a phosphatidylinositol kinase activity
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Synonyms
  • "1-phosphatidylinositol-5-phosphate kinase" BROAD
    "ATP:1-phosphatidyl-1D-myo-inositol-5-phosphate 4-phosphotransferase activity" RELATED[ EC:2 ]
    "PIP4K" EXACT
    "type II PIP kinase activity" NARROW[ EC:2 ]
Secondary IDs
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EC:2.7.1.149
MetaCyc:2.7.1.149-RXN
Reactome:R-HSA-1675776 "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane"
Reactome:R-HSA-6811522 "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus"
RHEA:12280
RHEA:55992