FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term dimethylargininase activity ID (Ontology) GO:0016403 (Gene Ontology)
Definition Catalysis of the reaction: N(G),N(G)-dimethyl-L-arginine + H2O = dimethylamine + L-citrulline.[ EC:3 ]
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Genes
 dimethylargininase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | dimethylargininase activity       1
Spanning Tree (Parents/Children)
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  hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
   |__hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
       |__dimethylargininase activity  1 rec.
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Is a hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
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Synonyms
  • "dimethylarginine dimethylaminohydrolase activity" RELATED[ EC:3 ]
    "N(G),N(G)-dimethylarginine dimethylaminohydrolase activity" RELATED[ EC:3 ]
    "NG,NG-dimethyl-L-arginine dimethylamidohydrolase activity" RELATED[ EC:3 ]
    "NG,NG-dimethylarginine dimethylaminohydrolase activity" RELATED[ EC:3 ]
Secondary IDs
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EC:3.5.3.18
MetaCyc:DIMETHYLARGININASE-RXN
Reactome:R-HSA-5693373 "DDAH1 hydrolyses ADMA to DMA and L-Cit"
RHEA:17305