FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
Help Close All Open All
General Information
Term pyrophosphatase activity ID (Ontology) GO:0016462 (Gene Ontology)
Definition Catalysis of the hydrolysis of a pyrophosphate bond (diphosphate bond) between two phosphate groups.
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       2
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 pyrophosphatase activity (all annotations which use CV term, excluding "NOT" statements)       1      2
     enables | pyrophosphatase activity       --       2
Spanning Tree (Parents/Children)
Only view relationship: 
  hydrolase activity, acting on acid anhydrides
   |__hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
       |__pyrophosphatase activity  445 rec.
           |__4-amino-5-hydroxymethyl-2-methylpyrimidine diphosphatase activity
           |__5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity 1 rec.
           |__5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity 1 rec.
           |__5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity
           |__acylphosphatase activity 7 rec.
           |__adenosine-tetraphosphatase activity
           |__ADP-ribose diphosphatase activity 4 rec.
           |__ADP-sugar pyrophosphatase activity
           |   |__ADP-glucose pyrophosphatase activity
           |   |__ADP-ribose pyrophosphatase activity
           |__all-trans-phytoene synthase activity
           |__apyrase activity
           |__bis(5'-adenosyl)-hexaphosphatase activity 1 rec.
           |__bis(5'-adenosyl)-pentaphosphatase activity 1 rec.
           |__bis(5'-adenosyl)-triphosphatase activity 1 rec.
           |__bis(5'-nucleosyl)-tetraphosphatase activity 1 rec.
           |   |__bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity 1 rec.
           |   |__bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity
           |__CDP-diacylglycerol diphosphatase activity
           |__CDP-glycerol diphosphatase activity
           |__coenzyme A diphosphatase activity 6 rec.
           |__diacylglycerol diphosphate phosphatase activity 1 rec.
           |__dihydroneopterin triphosphate pyrophosphohydrolase activity
           |__dinucleotide phosphatase activity 1 rec.
           |   |__FAD diphosphatase activity
           |   |__NAD+ diphosphatase activity
           |   |__NADH pyrophosphatase activity 1 rec.
           |   |__NADPH pyrophosphatase activity
           |__diphosphoinositol-polyphosphate diphosphatase activity 1 rec.
           |   |__inositol bisdiphosphate tetrakisphosphate diphosphatase activity(+)
           |   |__inositol diphosphate pentakisphosphate diphosphatase activity(+) 1 rec.
           |   |__inositol diphosphate tetrakisphosphate diphosphatase activity(+)
           |__DNA 5'-adenosine monophosphate hydrolase activity 1 rec.
           |__DNA-3'-diphospho-5'-guanosine diphosphatase activity 1 rec.
           |__endopolyphosphatase activity 1 rec.
           |__exopolyphosphatase activity 1 rec.
           |__GDP-mannose hydrolase activity
           |__guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity
           |__inorganic diphosphate phosphatase activity 1 rec.
           |__inorganic triphosphate phosphatase activity
           |__isoprenoid diphosphate phosphatase activity 1 rec.
           |   |__polyprenyl diphosphate phosphatase activity(+) 1 rec.
           |__mRNA 5'-diphosphatase activity 1 rec.
           |__mRNA 5'-triphosphate monophosphatase activity 1 rec.
           |__nucleoside diphosphate phosphatase activity 6 rec.
           |   |__8-hydroxy-dADP phosphatase activity
           |   |__8-oxo-dADP diphosphate phosphatase activity
           |   |__8-oxo-dGDP phosphatase activity 2 rec.
           |   |__8-oxo-GDP phosphatase activity 1 rec.
           |   |__ADP phosphatase activity 2 rec.
           |   |__CDP phosphatase activity
           |   |__dIDP phosphatase activity
           |   |__GDP phosphatase activity 2 rec.
           |   |__IDP phosphatase activity 1 rec.
           |   |__UDP phosphatase activity 2 rec.
           |__nucleoside triphosphate diphosphatase activity 4 rec.
           |   |__2-hydroxy-ATP hydrolase activity
           |   |__2-hydroxy-dATP hydrolase activity
           |   |__8-oxo-(d)RTP hydrolase activity
           |   |__8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity
           |   |__8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity
           |   |__ATP diphosphatase activity
           |   |__dATP diphosphatase activity
           |   |__dCTP diphosphatase activity
           |   |__dGTP diphosphatase activity
           |   |__dITP diphosphatase activity 1 rec.
           |   |__dTTP diphosphatase activity
           |   |__dUTP diphosphatase activity 1 rec.
           |   |__GTP diphosphatase activity
           |   |__ITP diphosphatase activity 1 rec.
           |   |__UTP diphosphatase activity
           |   |__XTP diphosphatase activity 1 rec.
           |__oligosaccharide-diphosphodolichol diphosphatase activity
           |__phosphoribosyl-ATP diphosphatase activity
           |__ribonucleoside triphosphate phosphatase activity 404 rec.
           |   |__ATP hydrolysis activity 234 rec.
           |   |__CTPase activity
           |   |__GTPase activity(+) 169 rec.
           |   |__ITPase activity
           |   |__TTPase activity
           |__RNA NAD-cap (NMN-forming) hydrolase activity
           |__thiamine diphosphate phosphatase activity
           |__thiamine triphosphate phosphatase activity
           |__UDP-2,3-diacylglucosamine hydrolase activity
           |__UDP-sugar diphosphatase activity 3 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
Part of
hide Synonyms & Secondary IDs
Synonyms
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-6810472 "NUDT13 hydrolyses AP6A to AP4 and ADP"