FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

peptide hormone processing

ID (Ontology)

GO:0016486 (Gene Ontology)

Definition

The generation of a mature peptide hormone by posttranslational processing of a prohormone.

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
peptide hormone processing (all annotations which use CV term, excluding "NOT" statements)
involved_in \| peptide hormone processing

Spanning Tree (Parents/Children)

metabolic process
 |__hormone metabolic process_______________________
regulation of hormone levels                        |
 |__hormone metabolic process_______________________|
protein processing                                  |
 |__signaling receptor ligand precursor processing__|
                                                    peptide hormone processing  19 rec.
                                                     |__angiotensin maturation 3 rec.
                                                     |__endothelin maturation
                                                     |__enkephalin processing
                                                     |__epidermal growth factor receptor ligand maturation 8 rec.
                                                     |__glucagon processing
                                                     |__insulin processing
                                                     |__islet amyloid polypeptide processing
                                                     |__nerve growth factor processing
                                                     |__patched ligand maturation 3 rec.
                                                     |__regulation of peptide hormone processing 1 rec.
                                                         |__negative regulation of peptide hormone processing 1 rec.
                                                         |__positive regulation of peptide hormone processing

Spanning Tree View Settings
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Relationships
Is a	hormone metabolic process signaling receptor ligand precursor processing
Part of
Synonyms & Secondary IDs
Synonyms

Secondary IDs

External Crossreferences & Linkouts
	Reactome:R-HSA-209952 "Peptide hormone biosynthesis" Reactome:R-HSA-400508 "Incretin synthesis, secretion, and inactivation" Reactome:R-HSA-422085 "Synthesis, secretion, and deacylation of Ghrelin"