FB2026_03 , released September 17, 2026
CV Term Report
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Term mitochondrial fatty acid beta-oxidation multienzyme complex ID (Ontology) GO:0016507 (Gene Ontology)
Definition A multienzyme complex possessing three activities in two subunits (alpha and beta) that catalyzes three steps of the fatty acid beta-oxidation cycle within the mitochondrial matrix. The alpha subunit comprises the enoyl-CoA hydratase (ECH) and 3-hydroxyacyl-CoA dehydrogenase (HACD) activities, and the beta subunit contains the acetyl-CoA C-acyltransferase (KACT)/thiolase activity.[ PubMed:29915090 ]
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Genes (FBgn)GO_CELLULAR_COMPONENT
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 mitochondrial fatty acid beta-oxidation multienzyme complex (all annotations which use CV term, excluding "NOT" statements)
     part_of | mitochondrial fatty acid beta-oxidation multienzyme complex       --
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mitochondrion
 |__mitochondrial matrix___________________________
 |__mitochondrial protein-containing complex_______|
protein-containing complex                         |
 |__mitochondrial protein-containing complex_______|
intracellular organelle lumen                      |
 |__mitochondrial matrix___________________________|
oxidoreductase complex                             |
 |__fatty acid beta-oxidation multienzyme complex__|
transferase complex                                |
 |__fatty acid beta-oxidation multienzyme complex__|
                                                   mitochondrial fatty acid beta-oxidation multienzyme complex  3 rec.
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Is a fatty acid beta-oxidation multienzyme complex
mitochondrial protein-containing complex
Part of mitochondrial matrix
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Synonyms
  • "fatty acid beta-oxidation multienzyme complex" BROAD
    "trifunctional enzyme" RELATED
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