FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term long-chain (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity ID (Ontology) GO:0016509 (Gene Ontology)
Definition Catalysis of the reaction: a long-chain (3S)-3-hydroxy fatty acyl-CoA + NAD+ = a long-chain 3-oxo-fatty acyl-CoA + H+ + NADH. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 long-chain (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity (all annotations which use CV term, excluding "NOT" statements)
     enables | long-chain (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity
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  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
   |__(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity
       |__long-chain (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity  1 rec.
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Is a (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity
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Synonyms
  • "beta-hydroxyacyl-CoA dehydrogenase activity" RELATED[ EC:1 ]
    "LCHAD" RELATED[ EC:1 ]
    "long-chain 3-hydroxyacyl coenzyme A dehydrogenase activity" RELATED[ EC:1 ]
    "long-chain-(S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase activity" RELATED[ EC:1 ]
    "long-chain-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity" BROAD
Secondary IDs
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EC:1.1.1.211
MetaCyc:1.1.1.211-RXN
RHEA:31159
RHEA:31167
RHEA:47428
RHEA:47440
RHEA:47456
RHEA:52656
RHEA:78727
RHEA:78731
RHEA:78739
RHEA:82931
RHEA:82999
RHEA:83031
RHEA:83075
RHEA:83079
RHEA:83139
RHEA:83215
RHEA:83327
RHEA:83363
RHEA:83379
RHEA:83395
RHEA:84411
RHEA:84415
RHEA:84427
RHEA:84671
RHEA:84675
RHEA:84679
RHEA:84691
RHEA:85131