FB2026_03 , released September 17, 2026
CV Term Report
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Term oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor ID (Ontology) GO:0016620 (Gene Ontology)
Definition Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces NAD or NADP.
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (all annotations which use CV term, excluding "NOT" statements)
     enables | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor       --
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  oxidoreductase activity
   |__oxidoreductase activity, acting on the aldehyde or oxo group of donors
       |__oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor  38 rec.
           |__3-chloroallyl aldehyde dehydrogenase activity
           |__4-formylbenzenesulfonate dehydrogenase (NAD+) activity
           |__acetaldehyde dehydrogenase (acetylating, NAD+) activity
           |__alcohol-forming long-chain fatty acyl-CoA reductase (NADP+) activity 17 rec.
           |__alcohol-forming very long-chain fatty acyl-CoA reductase (NADP+) activity 18 rec.
           |__aldehyde dehydrogenase [NAD(P)+] activity 11 rec.
           |   |__aldehyde dehydrogenase (NAD+) activity(+) 11 rec.
           |   |__aldehyde dehydrogenase (NADP+) activity(+)
           |   |__butanal dehydrogenase [NAD(P)+] activity
           |   |__coniferyl-aldehyde dehydrogenase [NAD(P)+] activity
           |   |__L-aminoadipate-semialdehyde dehydrogenase [NAD(P)+] activity 1 rec.
           |   |__malonate-semialdehyde dehydrogenase (acetylating, [NAD(P)+]) activity
           |   |__malonate-semialdehyde dehydrogenase [NAD(P)+] activity
           |__alpha-ketoester reductase (NADP+) activity
           |__aspartate-semialdehyde dehydrogenase (NADP+) activity
           |__cinnamoyl-CoA reductase (NADP+) activity
           |__delta1-pyrroline-5-carboxylate synthetase (NADP+) activity
           |__erythrose-4-phosphate dehydrogenase (NAD+) activity
           |__glutamate-5-semialdehyde dehydrogenase (NADP+) activity 1 rec.
           |__glutamyl-tRNA reductase (NADP+) activity
           |__glyceraldehyde-3-phosphate dehydrogenase (non-phosphorylating, [NAD(P)+] ) activity
           |   |__glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity
           |   |__glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity
           |__glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity 4 rec.
           |   |__glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity 4 rec.
           |   |__glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity
           |__glyoxylate dehydrogenase (acylating, NADP+) activity
           |__long-chain-fatty-acyl-CoA reductase (NADP+) activity
           |__methylmalonate-semialdehyde dehydrogenase (acylating, NAD+) activity 1 rec.
           |__N-acetyl-gamma-aminoadipyl-phosphate reductase (NADP+) activity
           |__N-acetyl-gamma-glutamyl-phosphate reductase (NADP+) activity
           |__phenylglyoxylate dehydrogenase (acylating, NAD+) activity
           |__pyruvate dehydrogenase (NADP+) activity
           |__succinate-semialdehyde dehydrogenase [NAD(P)+] activity 1 rec.
           |   |__succinate-semialdehyde dehydrogenase (NAD+) activity 1 rec.
           |   |__succinate-semialdehyde dehydrogenase (NADP+) activity
           |__vanillin dehydrogenase (NAD+) activity
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Is a oxidoreductase activity, acting on the aldehyde or oxo group of donors
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EC:1.2.1.-
Reactome:R-HSA-1222583 "MscR reduces nitrosomycothiol to ammonia"