FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor ID (Ontology) GO:0016624 (Gene Ontology)
Definition Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a disulfide.
Also Known As "oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulphide as acceptor"
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       6
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Relevant FlyBase reports
 Gene Groups Genes
 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor (all annotations which use CV term, excluding "NOT" statements)       1      6
     enables | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor       --       6
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  oxidoreductase activity
   |__oxidoreductase activity, acting on the aldehyde or oxo group of donors
       |__oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor  21 rec.
           |__2-oxoadipate dehydrogenase activity 3 rec.
           |__branched-chain 2-oxo acid dehydrogenase activity 4 rec.
           |__oxoglutarate dehydrogenase (succinyl-transferring) activity 6 rec.
           |__pyruvate dehydrogenase (acetyl-transferring) activity 7 rec.
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Is a oxidoreductase activity, acting on the aldehyde or oxo group of donors
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Synonyms
  • "oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulphide as acceptor" EXACT
Secondary IDs
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EC:1.2.4.-
Reactome:R-HSA-9858321 "DHTKD1 dimer decarboxylates 2-OA"
Reactome:R-HSA-9859148 "BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV"
Reactome:R-HSA-9865121 "BCKDHA or BCKDHB loss-of-function mutants don't synthesize BCAA-CoA"