FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor

ID (Ontology)

GO:0016624 (Gene Ontology)

Definition

Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a disulfide.

Also Known As

"oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulphide as acceptor"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Gene Groups	Genes
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor (all annotations which use CV term, excluding "NOT" statements)
enables \| oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	--

Spanning Tree (Parents/Children)

  oxidoreductase activity
   |__oxidoreductase activity, acting on the aldehyde or oxo group of donors
       |__oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor  21 rec.
           |__2-oxoadipate dehydrogenase activity 3 rec.
           |__branched-chain 2-oxo acid dehydrogenase activity 4 rec.
           |__oxoglutarate dehydrogenase (succinyl-transferring) activity 6 rec.
           |__pyruvate dehydrogenase (acetyl-transferring) activity 7 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	oxidoreductase activity, acting on the aldehyde or oxo group of donors
Part of
Synonyms & Secondary IDs
Synonyms
	"oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulphide as acceptor" EXACT
Secondary IDs

External Crossreferences & Linkouts
	EC:1.2.4.- Reactome:R-HSA-9858321 "DHTKD1 dimer decarboxylates 2-OA" Reactome:R-HSA-9859148 "BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV" Reactome:R-HSA-9865121 "BCKDHA or BCKDHB loss-of-function mutants don't synthesize BCAA-CoA"