FB2026_03 , released September 17, 2026
CV Term Report
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Term oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor ID (Ontology) GO:0016671 (Gene Ontology)
Definition Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide.
Also Known As"oxidoreductase activity, acting on sulphur group of donors, disulphide as acceptor"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor (all annotations which use CV term, excluding "NOT" statements)
     enables | oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor       --
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  oxidoreductase activity
   |__oxidoreductase activity, acting on a sulfur group of donors
       |__oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor  15 rec.
           |__adenylyl-sulfate reductase (glutathione) activity
           |__adenylyl-sulfate reductase (thioredoxin) activity
           |__enzyme-thiol transhydrogenase (glutathione-disulfide) activity
           |__glutathione-CoA-glutathione transhydrogenase activity
           |__glutathione-cystine transhydrogenase activity
           |__glutathione-homocystine transhydrogenase activity
           |__L-methionine (R)-S-oxide reductase activity
           |__L-methionine (S)-S-oxide reductase activity 1 rec.
           |__peptide-methionine (R)-S-oxide reductase activity 1 rec.
           |__peptide-methionine (S)-S-oxide reductase activity 1 rec.
           |__phosphoadenylyl-sulfate reductase (thioredoxin) activity
           |__protein-disulfide reductase (glutathione) activity
           |__protein-glutathione oxidoreductase (glutathione) activity 5 rec.
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Is a oxidoreductase activity, acting on a sulfur group of donors
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Synonyms
  • "oxidoreductase activity, acting on sulphur group of donors, disulphide as acceptor" EXACT
Secondary IDs
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EC:1.8.4.-
Reactome:R-HSA-9035484 "MPST and TXN2 enable the synthesis of disulfanide from CysS248-MPST"