FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term oxidoreductase activity, acting on single donors with incorporation of molecular oxygen ID (Ontology) GO:0016701 (Gene Ontology)
Definition Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and molecular oxygen is incorporated into a donor.[ EC:1 ]
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Genes
 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen (all annotations which use CV term, excluding "NOT" statements)       1
     enables | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen       1
Spanning Tree (Parents/Children)
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  catalytic activity
   |__oxidoreductase activity
       |__oxidoreductase activity, acting on single donors with incorporation of molecular oxygen  9 rec.
           |__inositol oxygenase activity 1 rec.
           |__oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)
           |   |__1,3,6,8-tetrahydroxynaphthalene monooxygenase (quinone-forming) activity
           |   |__2-oxoglutarate oxygenase/decarboxylase (ethylene-forming) activity
           |   |__arginine 2-monooxygenase activity
           |   |__Cypridina-luciferin 2-monooxygenase activity
           |   |__L-lysine 2-monooxygenase activity
           |   |__lactate 2-monooxygenase activity
           |   |__nitronate monooxygenase (FMN-linked) activity
           |   |__nitronate monooxygenase activity
           |   |__Oplophorus-luciferin 2-monooxygenase activity
           |   |__phenylalanine 2-monooxygenase activity
           |   |__Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity
           |   |__Renilla-luciferin 2-monooxygenase activity
           |   |__tryptophan 2-monooxygenase activity
           |   |__Watasenia-luciferin 2-monooxygenase activity
           |__oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 8 rec.
           |   |__1,2-dihydroxynaphthalene dioxygenase activity
           |   |__1-hydroxy-2-naphthoate 1,2-dioxygenase activity
           |   |__2,3-dihydroxy-p-cumate dioxygenase activity
           |   |__2,3-dihydroxybenzoate 2,3-dioxygenase activity
           |   |__2,3-dihydroxybenzoate 3,4-dioxygenase activity
           |   |__2,3-dihydroxybiphenyl 1,2-dioxygenase activity
           |   |__2,3-dihydroxyindole 2,3-dioxygenase activity
           |   |__2,4'-dihydroxyacetophenone dioxygenase activity
           |   |__2,5-dihydroxypyridine 5,6-dioxygenase activity
           |   |__3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity
           |   |__3,4-dihydroxyphenylacetate 2,3-dioxygenase activity
           |   |__3-carboxyethylcatechol 2,3-dioxygenase activity
           |   |__3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase activity
           |   |__3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity
           |   |__3-hydroxyanthranilate 3,4-dioxygenase activity
           |   |__4-hydroxymandelate synthase activity
           |   |__4-hydroxyphenylpyruvate dioxygenase activity 1 rec.
           |   |__5,6-dimethylbenzimidazole synthase activity
           |   |__7,8-dihydroxykynurenate 8,8a-dioxygenase activity
           |   |__9-cis-10'-apo-beta-carotenal cleavage oxygenase activity
           |   |__9-cis-beta-carotene 9',10'-cleavage oxygenase activity
           |   |__acetylacetone-cleaving enzyme activity
           |   |__acireductone dioxygenase (Ni2+-requiring) activity 1 rec.
           |   |__acireductone dioxygenase [iron(II)-requiring] activity 1 rec.
           |   |__all-trans-8'-apo-beta-carotenal 15,15'-oxygenase activity
           |   |__all-trans-beta-apo-10'-carotenal cleavage oxygenase activity
           |   |__apo-beta-carotenoid-14',13'-dioxygenase activity
           |   |__arachidonate 5-lipoxygenase activity
           |   |__arachidonate 8(R)-lipoxygenase activity
           |   |__arachidonate 8(S)-lipoxygenase activity
           |   |__arachidonate 12(R)-lipoxygenase activity
           |   |__arachidonate 12(S)-lipoxygenase activity
           |   |__arachidonate 15-lipoxygenase activity
           |   |__beta,beta-carotene-9',10'-cleaving oxygenase activity
           |   |__beta-carotene 15,15'-dioxygenase activity 1 rec.
           |   |__biphenyl-2,3-diol 1,2-dioxygenase activity
           |   |__caffeate 3,4-dioxygenase activity
           |   |__carotenoid dioxygenase activity(+) 1 rec.
           |   |__catechol 1,2-dioxygenase activity
           |   |__catechol 2,3-dioxygenase activity
           |   |__chloridazon-catechol dioxygenase activity
           |   |__chlorite O2-lyase activity
           |   |__cysteamine dioxygenase activity 1 rec.
           |   |__cysteine dioxygenase activity 1 rec.
           |   |__fatty acid alpha-dioxygenase activity
           |   |__gallate dioxygenase activity
           |   |__gentisate 1,2-dioxygenase activity
           |   |__homogentisate 1,2-dioxygenase activity 1 rec.
           |   |__hydroxyquinol 1,2-dioxygenase activity
           |   |__indole 2,3-dioxygenase activity
           |   |__indoleamine 2,3-dioxygenase activity
           |   |__L-tryptophan 2,3-dioxygenase activity 1 rec.
           |   |__lignostilbene alpha beta-dioxygenase activity
           |   |__linoleate 8R-lipoxygenase activity
           |   |__linoleate 9S-lipoxygenase activity
           |   |__linoleate 11-lipoxygenase activity
           |   |__linoleate 13S-lipoxygenase activity
           |   |__linolenate 9R-lipoxygenase activity
           |   |__protocatechuate 3,4-dioxygenase activity
           |   |__protocatechuate 4,5-dioxygenase activity
           |   |__pyrogallol 1,2-oxygenase activity
           |   |__quercetin 2,3-dioxygenase activity
           |   |__stizolobate synthase activity
           |   |__stizolobinate synthase activity
           |   |__sulfur dioxygenase activity 1 rec.
           |   |__sulfur oxygenase/reductase activity
           |   |__violaxanthin oxygenase activity
           |__tryptophan 2'-dioxygenase activity
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Synonyms
  • "oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, miscellaneous" NARROW
    "oxygenase" BROAD
Secondary IDs
hide External Crossreferences & Linkouts
EC:1.13.-.-
Reactome:R-HSA-2161951 "Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2"
Reactome:R-HSA-9018858 "ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE"
Reactome:R-HSA-9018859 "ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE"
Reactome:R-HSA-9018863 "ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE"
Reactome:R-HSA-9018894 "ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE"
Reactome:R-HSA-9020251 "ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA"
Reactome:R-HSA-9020255 "ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA"
Reactome:R-HSA-9020256 "ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA"
Reactome:R-HSA-9020259 "ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA"
Reactome:R-HSA-9020261 "Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA"
Reactome:R-HSA-9020264 "ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA"
Reactome:R-HSA-9020277 "ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA"
Reactome:R-HSA-9020278 "ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA"
Reactome:R-HSA-9020282 "ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA"
Reactome:R-HSA-9024997 "ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA"
Reactome:R-HSA-9025995 "ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3"
Reactome:R-HSA-9025996 "ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3"
Reactome:R-HSA-9025999 "ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3"
Reactome:R-HSA-9026005 "ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA"
Reactome:R-HSA-9026405 "ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4"
Reactome:R-HSA-9027532 "PTGS2 dimer oxidises DHA to 13-HDHA"
Reactome:R-HSA-9027607 "Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3"
Reactome:R-HSA-9027624 "ALOX5 oxidises DHA to 7-HDHA"
Reactome:R-HSA-9027627 "Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages)"
Reactome:R-HSA-9027628 "ALOX5 oxidises EPA to 5-HEPE"
Reactome:R-HSA-9027633 "ALOX5 oxidises DPAn-3 to 7-HDPAn-3"
Reactome:R-HSA-9028255 "PTGS2 dimer oxidises EPA to PGH3"