FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen ID (Ontology) GO:0016709 (Gene Ontology)
Definition Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.[ EC:1 ]
Comment
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Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Gene Groups Genes
 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen (all annotations which use CV term, excluding "NOT" statements)       1      1
     enables | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen       --       1
Spanning Tree (Parents/Children)
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oxidoreductase activity
 |__monooxygenase activity_________________________________________________________________________________
 |__oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen__|
                                                                                         oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen  7 rec.
                                                                                          |__(+)-taxifolin 5'-hydroxylase activity
                                                                                          |__(-)-menthol monooxygenase activity
                                                                                          |__(3E)-4,8-dimethyl-1,3,7-nonatriene synthase activity
                                                                                          |__(5alpha)-campestan-3-one hydroxylase activity
                                                                                          |__1-deoxy-11-oxopentalenate oxygenase activity
                                                                                          |__1-hydroxy-2-naphthoate hydroxylase activity
                                                                                          |__2,2',3-trihydroxybiphenyl monooxygenase activity
                                                                                          |__2,4-dichlorophenol 6-monooxygenase activity
                                                                                          |__2,6-dihydroxypyridine 3-monooxygenase activity
                                                                                          |__2-heptyl-3-hydroxy-4(1H)-quinolone synthase activity
                                                                                          |__2-hydroxybiphenyl 3-monooxygenase (NADH) activity
                                                                                          |__2-hydroxycyclohexanone 2-monooxygenase activity
                                                                                          |__2-hydroxyquinoline 8-monooxygenase activity
                                                                                          |__2-isopropylphenol monooxygenase activity
                                                                                          |__2-nitrophenol 2-monooxygenase activity
                                                                                          |__2-octaprenyl-6-methoxyphenol hydroxylase activity
                                                                                          |__2-polyprenylphenol 6-hydroxylase activity
                                                                                          |__2-propylphenol monooxygenase activity
                                                                                          |__3-(3-hydroxyphenyl)propionate hydroxylase activity
                                                                                          |__3-demethoxyubiquinone 3-hydroxylase (NADH) activity 1 rec.
                                                                                          |__3-hydroxy-2-methylpyridine-5-carboxylate monooxygenase [NAD(P)H] activity
                                                                                          |__3-hydroxybenzoate 4-monooxygenase activity
                                                                                          |__3-hydroxybenzoate 6-monooxygenase activity
                                                                                          |__3-hydroxyphenylacetate 6-hydroxylase activity
                                                                                          |__4,8,12-trimethyltrideca-1,3,7,11-tetraene synthase activity
                                                                                          |__4-aminobenzoate 1-monooxygenase activity
                                                                                          |__4-hydroxyacetophenone monooxygenase activity
                                                                                          |__4-hydroxybenzoate 1-hydroxylase activity
                                                                                          |__4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity
                                                                                          |   |__4-hydroxybenzoate 3-monooxygenase (NADH) activity
                                                                                          |   |__4-hydroxybenzoate 3-monooxygenase (NADPH) activity
                                                                                          |__4-hydroxybenzoate 3-monooxygenase activity
                                                                                          |__4-hydroxyphenylacetate 1-monooxygenase activity
                                                                                          |__4-hydroxyquinoline 3-monooxygenase activity
                                                                                          |__4-nitrocatechol 4-monooxygenase activity
                                                                                          |__4-nitrophenol 2-monooxygenase activity
                                                                                          |__4-nitrophenol 4-monooxygenase activity
                                                                                          |__4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol-4alpha-methyl oxidase activity
                                                                                          |__4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol-methyl oxidase activity
                                                                                          |__5-methylphenazine-1-carboxylate 1-monooxygenase (NADH) activity
                                                                                          |__5-pyridoxate dioxygenase activity
                                                                                          |__6-hydroxynicotinate 3-monooxygenase activity
                                                                                          |__6-oxocineole dehydrogenase activity
                                                                                          |__albendazole monooxygenase activity
                                                                                          |__alkene monooxygenase activity
                                                                                          |__alpha-pinene monooxygenase (NADH) activity
                                                                                          |__anandamide epoxidase activity
                                                                                          |   |__anandamide 8,9 epoxidase activity
                                                                                          |   |__anandamide 11,12 epoxidase activity
                                                                                          |   |__anandamide 14,15 epoxidase activity
                                                                                          |__anhydrotetracycline monooxygenase activity
                                                                                          |__anthranilate 3-monooxygenase (deaminating) activity
                                                                                          |__anthraniloyl-CoA monooxygenase activity
                                                                                          |__apigenin-7,4'-dimethyl ether 6-hydroxylase activity
                                                                                          |__benzoyl-CoA 3-monooxygenase activity
                                                                                          |__chlorophyllide a oxygenase activity
                                                                                          |__cyclohexanone monooxygenase activity
                                                                                          |__cyclopentanone monooxygenase activity
                                                                                          |__dimethyl sulfide monooxygenase activity
                                                                                          |__dimethylsulfoxide oxygenase activity
                                                                                          |__F-actin monooxygenase activity 1 rec.
                                                                                          |__FAD-dependent urate hydroxylase activity
                                                                                          |__fluorescent chlorophyll catabolite monooxygenase (deformylase) activity
                                                                                          |__genkwanin 6-hydroxylase activity
                                                                                          |__hydroxyphenylacetonitrile 2-monooxygenase activity
                                                                                          |__hypotaurine monooxygenase activity 2 rec.
                                                                                          |__imidazoleacetate 4-monooxygenase activity
                                                                                          |__indole-3-pyruvate monooxygenase activity
                                                                                          |__ketosteroid monooxygenase activity
                                                                                          |__kynurenine 3-monooxygenase activity 1 rec.
                                                                                          |__L-lysine 6-monooxygenase (NADPH) activity
                                                                                          |__leukotriene-E4 20-monooxygenase activity
                                                                                          |__limonene 1,2-monooxygenase [NAD(P)H) activity
                                                                                          |__magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity
                                                                                          |__melilotate 3-monooxygenase activity
                                                                                          |__methane monooxygenase [NAD(P)H] activity
                                                                                          |__methanesulfonate monooxygenase activity
                                                                                          |__N,N-dimethylaniline monooxygenase activity 2 rec.
                                                                                          |__nitric-oxide synthase activity 1 rec.
                                                                                          |__oleate 12-hydroxylase activity
                                                                                          |__orcinol 2-monooxygenase activity
                                                                                          |__pentachlorophenol monooxygenase activity
                                                                                          |__phenol 2-monooxygenase activity
                                                                                          |__phenylacetone monooxygenase activity
                                                                                          |__phenylacetyl-CoA 1,2-epoxidase activity
                                                                                          |__precorrin-3B synthase activity
                                                                                          |__pyrrole-2-carboxylate monooxygenase (NADH) activity
                                                                                          |__questin monooxygenase (NADPH) activity
                                                                                          |__sakuranetin 6-hydroxylase activity
                                                                                          |__salicylate 1-monooxygenase activity
                                                                                          |__salicylate 5-hydroxylase (NADH) activity
                                                                                          |__senecionine N-oxygenase activity
                                                                                          |__syn-pimaradiene 6beta-hydroxylase activity
                                                                                          |__taxifolin 8-monooxygenase activity
                                                                                          |__taxoid 14-beta-hydroxylase activity
                                                                                          |__toluene 2-monooxygenase activity
                                                                                          |__toluene 4-monooxygenase activity
                                                                                          |__toluene-sulfonate methyl-monooxygenase activity
                                                                                          |__trans-cinnamate 2-monooxygenase activity
                                                                                          |__tri-(coumaroyl or caffeoyl) spermidine meta-hydroxylase activity
                                                                                          |   |__dicoumaroyl monocaffeoyl spermidine meta-hydroxylase activity
                                                                                          |   |__monocoumaroyl dicaffeoyl spermidine meta-hydroxylase activity
                                                                                          |   |__tricoumaroylspermidine meta-hydroxylase activity
                                                                                          |__tri-(feruloyl or hydroxyferuloyl) spermidine meta-hydroxylase activity
                                                                                          |   |__diferuloyl mono-(hydroxyferuloyl) spermidine meta-hydroxylase activity
                                                                                          |   |__monoferuloyl di-(hydroxyferuloyl) spermidine meta-hydroxylase activity
                                                                                          |   |__triferuloylspermidine meta-hydroxylase activity
                                                                                          |__trimethylamine monooxygenase activity
                                                                                          |__trimethyluric acid monooxygenase activity
                                                                                          |__vanillate monooxygenase activity
                                                                                          |__zeaxanthin 2-beta-hydroxylase activity
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Is a monooxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
Part of
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Synonyms
  • "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen" RELATED
Secondary IDs
hide External Crossreferences & Linkouts
EC:1.14.13.-
Reactome:R-HSA-211951 "CYP1B1 4-hydroxylates EST17b"
Reactome:R-HSA-2162187 "COQ6 hydroxylates DHB"
Reactome:R-HSA-2162194 "COQ7:COQ9 octamer hydroxylates DMQ10H2"
Reactome:R-HSA-6786239 "CYP4V2 omega-hydroxylates DHA to HDoHE"