FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term acid-thiol ligase activity ID (Ontology) GO:0016878 (Gene Ontology)
Definition Catalysis of the joining of an acid and a thiol via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.[ EC:6 ]
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Full annotation statements 
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 Genes
 acid-thiol ligase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | acid-thiol ligase activity       1
Spanning Tree (Parents/Children)
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  ligase activity
   |__ligase activity, forming carbon-sulfur bonds
       |__acid-thiol ligase activity  36 rec.
           |__2,3-dihydroxybenzoate--[aryl-carrier protein] ligase activity
           |__[citrate (pro-3S)-lyase] ligase activity
           |__CoA-ligase activity 35 rec.
           |   |__(E)-caffeate-CoA ligase activity
           |   |__2-furoate-CoA ligase activity
           |   |__2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity
           |   |__3-alpha,7-alpha-dihydroxy-5-beta-cholestanate-CoA ligase activity
           |   |__3-hydroxypropionyl-CoA synthetase activity
           |   |__4-chlorobenzoate-CoA ligase activity
           |   |__4-coumarate-CoA ligase activity
           |   |__4-hydroxybenzoate-CoA ligase activity
           |   |__6-carboxyhexanoate-CoA ligase activity
           |   |__acetate-CoA ligase (ADP-forming) activity
           |   |__acetoacetate-CoA ligase activity
           |   |__acetyl-CoA synthetase activity 3 rec.
           |   |__acid-CoA ligase (GDP-forming) activity
           |   |__anthranilate-CoA ligase activity
           |   |__benzoate-CoA ligase activity
           |   |__biotin-CoA ligase activity
           |   |__carnitine-CoA ligase activity
           |   |__cholate-CoA ligase activity
           |   |__citrate-CoA ligase activity
           |   |__crotonobetaine-CoA ligase activity
           |   |__dicarboxylate-CoA ligase activity
           |   |__fatty acid-CoA ligase activity(+) 25 rec.
           |   |__glutarate-CoA ligase activity
           |   |__malate-CoA ligase activity
           |   |__malonyl-CoA synthetase activity 1 rec.
           |   |__o-succinylbenzoate-CoA ligase activity
           |   |__oxalate-CoA ligase activity
           |   |__perillic acid-CoA ligase (AMP-forming) activity
           |   |__phenylacetate-CoA ligase activity
           |   |__phytanate-CoA ligase activity
           |   |__pristanate-CoA ligase activity
           |   |__succinate-CoA ligase activity(+) 7 rec.
           |   |__trans-cinnamate-CoA ligase activity
           |   |__trans-feruloyl-CoA synthase activity
           |__D-alanine [D-alanyl carrier protein] ligase activity
           |__fatty acid ligase activity 25 rec.
               |__fatty acid-CoA ligase activity(+) 25 rec.
               |__long-chain fatty acid [acyl-carrier-protein] ligase activity
               |__long-chain fatty acid--protein ligase activity
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Is a ligase activity, forming carbon-sulfur bonds
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Synonyms
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EC:6.2.1.-