FB2026_03 , released September 17, 2026
CV Term Report
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Term ligase activity, forming carbon-nitrogen bonds ID (Ontology) GO:0016879 (Gene Ontology)
Definition Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.[ EC:6 ]
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 ligase activity, forming carbon-nitrogen bonds (all annotations which use CV term, excluding "NOT" statements)
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  catalytic activity
   |__ligase activity
       |__ligase activity, forming carbon-nitrogen bonds  45 rec.
           |__5-(carboxyamino)imidazole ribonucleotide synthase activity
           |__acid-amino acid ligase activity 20 rec.
           |   |__2,3-dihydroxybenzoate-serine ligase activity
           |   |__aerobactin synthase activity
           |   |__amino acid ligation activity by nonribosomal peptide synthase
           |   |__carnosine synthase activity
           |   |__coenzyme F420-0 gamma-glutamyl ligase activity(+)
           |   |__coenzyme F420-2 alpha-glutamyl ligase activity
           |   |__cyanophycin synthetase activity(+)
           |   |__cyclopeptine synthase activity
           |   |__D-alanine-alanyl-poly(glycerolphosphate) ligase activity
           |   |__D-alanine-D-alanine ligase activity
           |   |__D-alanine-D-serine ligase activity
           |   |__dihydrofolate synthase activity
           |   |__gamma-glutamylhistamine synthase activity
           |   |__glutamate-cysteine ligase activity 2 rec.
           |   |__glutathione synthase activity 2 rec.
           |   |__homocarnosine synthase activity
           |   |__homoglutathione synthase activity
           |   |__indole-3-acetic acid amido synthetase activity(+)
           |   |__jasmonoyl-L-amino acid ligase activity
           |   |__L-amino-acid alpha-ligase activity
           |   |__L-propargylglycine--L-glutamate ligase activity
           |   |__N-(4-aminobenzoyl)-L-glutamate synthetase activity
           |   |__N-(4-hydroxybenzoyl)-L-glutamate synthetase activity
           |   |__N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase activity
           |   |__N-benzoyl-L-glutamate synthetase activity
           |   |__N-vanillate-L-glutamate synthetase activity
           |   |__pantoate-beta-alanine ligase activity
           |   |__phosphopantothenate--cysteine ligase activity 1 rec.
           |   |__phosphoribosylaminoimidazolesuccinocarboxamide synthase activity 1 rec.
           |   |__protein-glutamic acid ligase activity(+) 8 rec.
           |   |__protein-glycine ligase activity(+) 3 rec.
           |   |__tetrahydrofolylpolyglutamate synthase activity 2 rec.
           |   |__tubulin-tyrosine ligase activity
           |   |__tyrosine-arginine ligase activity
           |   |__UDP-N-acetylmuramate-L-alanine ligase activity
           |   |__UDP-N-acetylmuramate-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate ligase activity
           |   |__UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--D-lysine ligase activity
           |   |__UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity
           |   |__UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
           |   |__UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
           |   |__UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity
           |   |__UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
           |__acid-ammonia (or amide) ligase activity 4 rec.
           |   |__4-methyleneglutamate-ammonia ligase activity
           |   |__8-demethylnovobiocate synthase activity
           |   |__adenosylcobinamide-phosphate synthase activity
           |   |__ammonia ligase activity(+) 2 rec.
           |   |__aspartate-ammonia ligase (ADP-forming) activity
           |   |__cysteine-glucosaminylinositol ligase activity
           |   |__D-aspartate ligase activity
           |   |__diphthine-ammonia ligase activity 1 rec.
           |   |__glutamate-ethylamine ligase activity
           |   |__glutamate-putrescine ligase activity
           |   |__glutathionylspermidine synthase activity
           |   |__lipoate-protein ligase activity
           |   |__NAD+ synthase activity
           |   |__phosphoribosylglycinamide formyltransferase 2 activity
           |   |__trypanothione synthase activity
           |__adenylosuccinate synthase activity 1 rec.
           |__argininosuccinate synthase activity 1 rec.
           |__beta-alanyl amine synthase activity 1 rec.
           |__biotin carboxylase activity
           |__biotin--[biotin carboxyl-carrier protein] ligase activity 1 rec.
           |__carbamoyl-phosphate synthase (ammonia) activity
           |__carbon-nitrogen ligase activity, with glutamine as amido-N-donor 9 rec.
           |   |__adenosylcobyric acid synthase (glutamine-hydrolyzing) activity
           |   |__asparagine synthase (glutamine-hydrolyzing) activity 1 rec.
           |   |__asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity
           |   |__carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity 1 rec.
           |   |__carbon-nitrogen ligase activity on lipid II
           |   |__cobyrinic acid a,c-diamide synthase activity
           |   |__glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity 3 rec.
           |   |__GMP synthase (glutamine-hydrolyzing) activity(+) 1 rec.
           |   |__hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) activity
           |   |__NAD+ synthase (glutamine-hydrolyzing) activity 1 rec.
           |   |__phosphoribosylformylglycinamidine synthase activity 1 rec.
           |__citrate-L-glutamate ligase activity
           |__CTP synthase activity 1 rec.
           |__cyclo-ligase activity 3 rec.
           |   |__(carboxyethyl)arginine beta-lactam-synthase activity
           |   |__5-formyltetrahydrofolate cyclo-ligase activity 1 rec.
           |   |__dethiobiotin synthase activity
           |   |__phosphoribosylformylglycinamidine cyclo-ligase activity 1 rec.
           |__formate-dihydrofolate ligase activity
           |__formate-tetrahydrofolate ligase activity 1 rec.
           |__glutamate-methylamine ligase activity
           |__GMP synthase activity 1 rec.
           |__imidazoleacetate-phosphoribosyldiphosphate ligase activity
           |__indole-3-acetyl-glycine synthetase activity
           |__indole-3-acetyl-isoleucine synthetase activity
           |__indole-3-acetyl-methionine synthetase activity
           |__N-acetyl-L-aspartate-L-glutamate ligase activity
           |__nicotinate phosphoribosyltransferase activity 1 rec.
           |__phosphoribosylamine-glycine ligase activity 1 rec.
           |__ribose-5-phosphate-ammonia ligase activity
           |__tRNA(Ile)-lysidine synthase activity
           |__urea carboxylase activity
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  • "other carbon-nitrogen ligase activity" NARROW
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EC:6.3.-.-