FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term protein sumoylation ID (Ontology) GO:0016925 (Gene Ontology)
Definition The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein.[ PubMed:11265250 ]
Also Known As"protein sumolation" ; "small ubiquitin-related protein 1 conjugation" ; "SUMO-protein conjugation" (for all, see Synonyms field below)
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 protein sumoylation (all annotations which use CV term, excluding "NOT" statements)
     involved_in | protein sumoylation       --
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protein modification process
 |__peptidyl-lysine modification______________________________
protein modification by small protein conjugation or removal  |
 |__protein modification by small protein conjugation_________|
                                                              protein sumoylation  17 rec.
                                                               |__protein autosumoylation
                                                               |__regulation of protein sumoylation 3 rec.
                                                                   |__negative regulation of protein sumoylation 3 rec.
                                                                   |__positive regulation of protein sumoylation
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Is a peptidyl-lysine modification
protein modification by small protein conjugation
Part of
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Synonyms
  • "protein sumolation" EXACT
    "small ubiquitin-related protein 1 conjugation" EXACT
    "Smt3-protein conjugation" RELATED
    "Smt3p-protein conjugation" RELATED
    "SUMO-protein conjugation" EXACT
    "sumoylation" EXACT
Secondary IDs
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Reactome:R-HSA-2990846 "SUMOylation"
Wikipedia:SUMO_protein