FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term 6-phosphogluconolactonase activity ID (Ontology) GO:0017057 (Gene Ontology)
Definition Catalysis of the reaction: 6-O-phosphono-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H+.[ EC:3 ]
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 6-phosphogluconolactonase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | 6-phosphogluconolactonase activity
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  hydrolase activity, acting on ester bonds
   |__carboxylic ester hydrolase activity
       |__6-phosphogluconolactonase activity  1 rec.
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Is a carboxylic ester hydrolase activity
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Synonyms
  • "6-PGL" RELATED[ EC:3 ]
    "6-phospho-D-glucono-1,5-lactone lactonohydrolase activity" RELATED[ EC:3 ]
    "phosphogluconolactonase activity" RELATED[ EC:3 ]
Secondary IDs
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EC:3.1.1.31
KEGG_REACTION:R02035
MetaCyc:6PGLUCONOLACT-RXN
Reactome:R-HSA-71296 "PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate"
RHEA:12556