FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term single-strand selective uracil DNA N-glycosylase activity ID (Ontology) GO:0017065 (Gene Ontology)
Definition Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA.[ PubMed:9224623 ]
Also Known As"single-strand selective monofunctional uracil-DNA glycosylase activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 single-strand selective uracil DNA N-glycosylase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | single-strand selective uracil DNA N-glycosylase activity
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  deaminated base DNA N-glycosylase activity
   |__uracil DNA N-glycosylase activity
       |__single-strand selective uracil DNA N-glycosylase activity  1 rec.
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Is a uracil DNA N-glycosylase activity
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Synonyms
  • "single-strand selective monofunctional uracil-DNA glycosylase activity" EXACT
Secondary IDs
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Reactome:R-HSA-110221 "Cleavage of uracil by SMUG1 glycosylase"