FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term ribonucleoside triphosphate phosphatase activity ID (Ontology) GO:0017111 (Gene Ontology)
Definition Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate.
Also Known As"NTPase activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 ribonucleoside triphosphate phosphatase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | ribonucleoside triphosphate phosphatase activity       --
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  hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
   |__pyrophosphatase activity
       |__ribonucleoside triphosphate phosphatase activity  435 rec.
           |__ATP hydrolysis activity 258 rec.
           |__CTPase activity
           |__GTPase activity 176 rec.
           |   |__G protein activity 11 rec.
           |   |__GTPase motor activity(+)
           |   |__GTPase-dependent fusogenic activity 2 rec.
           |__ITPase activity
           |__TTPase activity
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Is a pyrophosphatase activity
Part of
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Synonyms
  • "apyrase activity" BROAD
    "NTPase activity" EXACT
    "nucleoside 5-triphosphatase activity" BROAD[ EC:3 ]
    "nucleoside triphosphatase activity" BROAD
    "nucleoside triphosphate hydrolase activity" BROAD
    "nucleoside triphosphate phosphatase activity" BROAD
    "nucleoside triphosphate phosphohydrolase activity" RELATED
    "nucleoside-5-triphosphate phosphohydrolase activity" RELATED
    "nucleoside-triphosphatase activity" BROAD
Secondary IDs
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EC:3.6.1.15
MetaCyc:NUCLEOSIDE-TRIPHOSPHATASE-RXN
Reactome:R-HSA-8850846 "NTPDase1 hydrolyzes nucleoside triphosphates"
Reactome:R-HSA-8851089 "NTPDase2 hydrolyzes nucleoside triphosphates"
Reactome:R-HSA-8851110 "NTPDase3 hydrolyzes nucleoside triphosphates"
Reactome:R-HSA-8851234 "NTPDase4 hydrolyzes nucleoside triphosphates"
Reactome:R-HSA-8851494 "NTPDase7 hydrolyzes nucleoside triphosphates"
Reactome:R-HSA-8851538 "NTPDase8 hydrolyzes nucleoside triphosphates"
RHEA:23680
RHEA:64900
RHEA:65580