FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term diphthine-ammonia ligase activity ID (Ontology) GO:0017178 (Gene Ontology)
Definition Catalysis of the reaction: ATP + diphthine + NH4 = ADP + diphthamide + H+ + phosphate.[ EC:6 ]
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 diphthine-ammonia ligase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | diphthine-ammonia ligase activity
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  ligase activity, forming carbon-nitrogen bonds
   |__acid-ammonia (or amide) ligase activity
       |__diphthine-ammonia ligase activity  1 rec.
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Is a acid-ammonia (or amide) ligase activity
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Synonyms
  • "diphthamide synthase activity" RELATED[ EC:6 ]
    "diphthamide synthetase activity" RELATED[ EC:6 ]
    "diphthine:ammonia ligase (ADP-forming)" RELATED[ EC:6 ]
Secondary IDs
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EC:6.3.1.14
KEGG_REACTION:R03613
MetaCyc:DIPHTINE--AMMONIA-LIGASE-RXN
Reactome:R-HSA-5358475 "DPH6 ligates ammonium to diphthine-EEF2"
RHEA:19753