FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

ammonia assimilation cycle

ID (Ontology)

GO:0019676 (Gene Ontology)

Definition

The pathway by which ammonia is processed and incorporated into a cell. In an energy-rich (glucose-containing), nitrogen-poor environment, glutamine synthetase and glutamate synthase form an ammonia assimilatory cycle, in which ammonia is incorporated into L-glutamate to form L-glutamine, which then combines with alpha-ketoglutarate to regenerate L-glutamate. This ATP-dependent cycle is essential for nitrogen-limited growth and for steady-state growth with some sources of nitrogen.

Also Known As

"glutamate metabolic process via glutamine and ammonia" ; "glutamate metabolism via glutamine and ammonia"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
ammonia assimilation cycle (all annotations which use CV term, excluding "NOT" statements)
involved_in \| ammonia assimilation cycle

Spanning Tree (Parents/Children)

amino acid metabolic process
 |__glutamate metabolic process_____________
metabolic process                           |
 |__nutrient assimilation___________________|
response to nutrient levels                 |
 |__nitrogen utilization____________________|
dicarboxylic acid metabolic process         |
 |__glutamate metabolic process_____________|
intracellular nitrogen homeostasis          |
 |__nitrogen utilization____________________|
proteinogenic amino acid metabolic process  |
 |__L-glutamine metabolic process___________|
                                            ammonia assimilation cycle  1 rec.
                                             |__regulation of ammonia assimilation cycle
                                                 |__negative regulation of ammonia assimilation cycle
                                                 |__positive regulation of ammonia assimilation cycle

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	glutamate metabolic process L-glutamine metabolic process nitrogen utilization nutrient assimilation
Part of
Synonyms & Secondary IDs
Synonyms
	"glutamate metabolic process via glutamine and ammonia" EXACT "glutamate metabolism via glutamine and ammonia" EXACT
Secondary IDs

External Crossreferences & Linkouts
	MetaCyc:AMMASSIM-PWY MetaCyc:PWY-3282 MetaCyc:PWY-6963 MetaCyc:PWY-6964