FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

NEDD8 activating enzyme activity

ID (Ontology)

GO:0019781 (Gene Ontology)

Definition

Catalysis of the initiation of the NEDD8 (RUB1) conjugation cascade.[ PubMed:12646924 ]

Also Known As

"RUB1 activating enzyme activity"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Gene Groups	Genes
NEDD8 activating enzyme activity (all annotations which use CV term, excluding "NOT" statements)
contributes_to \| NEDD8 activating enzyme activity	--
enables \| NEDD8 activating enzyme activity	--

Spanning Tree (Parents/Children)

ligase activity, forming carbon-sulfur bonds__
catalytic activity, acting on a protein_______|
ATP-dependent activity________________________|
                                              ubiquitin-like modifier activating enzyme activity
                                               |__NEDD8 activating enzyme activity  3 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	ubiquitin-like modifier activating enzyme activity
Part of
Synonyms & Secondary IDs
Synonyms
	"RUB1 activating enzyme activity" EXACT
Secondary IDs

External Crossreferences & Linkouts
	EC:6.2.1.64