FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

ubiquitin-like protein peptidase activity

ID (Ontology)

GO:0019783 (Gene Ontology)

Definition

An isopeptidase activity that cleaves ubiquitin or ubiquitin-like proteins (ULP; e.g. ATG8, ISG15, NEDD8, SUMO) from target proteins.[ PubMed:19489724 ]

Also Known As

"small conjugating protein-specific isopeptidase activity" ; "small conjugating protein-specific protease activity" ; "ubiquitin-like hydrolase activity" (for all, see Synonyms field below)

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

There are no annotations using this term.

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Gene Groups
ubiquitin-like protein peptidase activity (all annotations which use CV term, excluding "NOT" statements)

Spanning Tree (Parents/Children)

hydrolase activity_______________________
catalytic activity, acting on a protein__|
                                         peptidase activity
                                          |__ubiquitin-like protein peptidase activity  78 rec.
                                              |__deNEDDylase activity 8 rec.
                                              |   |__cysteine-type deNEDDylase activity 2 rec.
                                              |   |__metal-dependent deNEDDylase activity 2 rec.
                                              |__deSUMOylase activity 5 rec.
                                              |__deubiquitinase activity 60 rec.
                                              |   |__cysteine-type deubiquitinase activity(+) 47 rec.
                                              |   |__histone deubiquitinase activity(+)
                                              |   |__K11-linked deubiquitinase activity
                                              |   |__K48-linked deubiquitinase activity 7 rec.
                                              |   |__K63-linked deubiquitinase activity 7 rec.
                                              |   |__metal-dependent deubiquitinase activity 8 rec.
                                              |__deUFMylase activity 3 rec.
                                              |__ISG15-specific peptidase activity
                                              |__ubiquitin-like protein-specific endopeptidase activity 2 rec.
                                                  |__SUMO-specific endopeptidase activity 2 rec.

Spanning Tree View Settings
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Relationships
Is a	peptidase activity
Part of
Synonyms & Secondary IDs
Synonyms
	"small conjugating protein-specific isopeptidase activity" EXACT "small conjugating protein-specific protease activity" EXACT "ubiquitin-like hydrolase activity" EXACT "ubiquitin-like protein-specific isopeptidase activity" EXACT "ubiquitin-like protein-specific protease activity" EXACT "ubiquitin-like specific protease activity" NARROW "ubiquitin-like-protein-specific protease activity" NARROW "ubiquitin-specific protease activity involved in negative regulation of ERAD pathway" NARROW "ubiquitin-specific protease activity involved in positive regulation of ERAD pathway" NARROW "ubiquitinyl-like hydrolase activity" EXACT
Secondary IDs

External Crossreferences & Linkouts