FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term ubiquitin-like protein transferase activity ID (Ontology) GO:0019787 (Gene Ontology)
Definition Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y = Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein.[ PubMed:10806345 PubMed:10884686 ]
Also Known As"small conjugating protein transferase activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 ubiquitin-like protein transferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | ubiquitin-like protein transferase activity       --
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catalytic activity
 |__catalytic activity, acting on a protein__
acyltransferase activity                     |
 |__aminoacyltransferase activity____________|
                                             ubiquitin-like protein transferase activity  236 rec.
                                              |__Atg12 transferase activity 2 rec.
                                              |   |__Atg12 conjugating enzyme activity 1 rec.
                                              |   |__Atg12 ligase activity
                                              |__FAT10 transferase activity
                                              |   |__FAT10 conjugating enzyme activity
                                              |   |__FAT10 ligase activity
                                              |__ISG15 transferase activity
                                              |   |__ISG15 conjugating enzyme activity
                                              |   |__ISG15 ligase activity
                                              |__NEDD8 transferase activity 9 rec.
                                              |   |__NEDD8 conjugating enzyme activity 1 rec.
                                              |   |__NEDD8 ligase activity 4 rec.
                                              |__Pup transferase activity
                                              |   |__Pup conjugating enzyme activity
                                              |   |__Pup ligase activity
                                              |__SUMO transferase activity 15 rec.
                                              |   |__SUMO conjugating enzyme activity 1 rec.
                                              |   |__SUMO ligase activity(+) 7 rec.
                                              |__ubiquitin-like protein conjugating enzyme activity 34 rec.
                                              |   |__Atg8-family conjugating enzyme activity 2 rec.
                                              |   |__Atg12 conjugating enzyme activity 1 rec.
                                              |   |__FAT10 conjugating enzyme activity
                                              |   |__ISG15 conjugating enzyme activity
                                              |   |__NEDD8 conjugating enzyme activity 1 rec.
                                              |   |__Pup conjugating enzyme activity
                                              |   |__SUMO conjugating enzyme activity 1 rec.
                                              |   |__ubiquitin conjugating enzyme activity 28 rec.
                                              |   |__UFM1 conjugating enzyme activity 1 rec.
                                              |   |__URM1 conjugating enzyme activity
                                              |__ubiquitin-like protein ligase activity 188 rec.
                                              |   |__Atg8-family ligase activity 3 rec.
                                              |   |__Atg12 ligase activity
                                              |   |__FAT10 ligase activity
                                              |   |__ISG15 ligase activity
                                              |   |__NEDD8 ligase activity 4 rec.
                                              |   |__Pup ligase activity
                                              |   |__SUMO ligase activity(+) 7 rec.
                                              |   |__ubiquitin protein ligase activity(+) 177 rec.
                                              |   |__UFM1 ligase activity 1 rec.
                                              |   |__URM1 ligase activity
                                              |__ubiquitin-protein transferase activity 207 rec.
                                              |   |__ubiquitin conjugating enzyme activity 28 rec.
                                              |   |__ubiquitin protein ligase activity(+) 177 rec.
                                              |__UFM1 transferase activity 3 rec.
                                              |   |__UFM1 conjugating enzyme activity 1 rec.
                                              |   |__UFM1 ligase activity 1 rec.
                                              |__URM1 transferase activity
                                                  |__URM1 conjugating enzyme activity
                                                  |__URM1 ligase activity
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Is a aminoacyltransferase activity
catalytic activity, acting on a protein
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Synonyms
  • "E2" BROAD
    "E3" RELATED
    "small conjugating protein ligase activity" NARROW
    "small conjugating protein transferase activity" EXACT
    "small protein conjugating enzyme activity" NARROW
    "ubiquitin-like conjugating enzyme activity" NARROW
    "ubiquitin-like-protein ligase activity" NARROW
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-5678490 "ATG16L1 complex transfers LC3 from ATG3 to PE"
Reactome:R-HSA-688137 "RIP2 is K63 polyubiquitinated"