FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term NEDD8 transferase activity ID (Ontology) GO:0019788 (Gene Ontology)
Definition Catalysis of the transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y = Y-NEDD8 + X, where both X-NEDD8 and Y-NEDD8 are covalent linkages.
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 NEDD8 transferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | NEDD8 transferase activity       --
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aminoacyltransferase activity____________
catalytic activity, acting on a protein__|
                                         ubiquitin-like protein transferase activity
                                          |__NEDD8 transferase activity  9 rec.
                                              |__NEDD8 conjugating enzyme activity 1 rec.
                                              |__NEDD8 ligase activity 4 rec.
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Is a ubiquitin-like protein transferase activity
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Synonyms
  • "Hub1 conjugating enzyme activity" RELATED
    "NEDD8 conjugating enzyme activity" RELATED
    "RUB1 conjugating enzyme activity" RELATED
Secondary IDs
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Reactome:R-HSA-8951648 "NEDD8 covalently binds catalytic cysteine of UBA3:NAE1"
Reactome:R-HSA-8951661 "Transfer of NEDD8 to AcM-UBE2M"
Reactome:R-HSA-8951764 "Transfer of NEDD8 to AcM-UBE2F"
Reactome:R-HSA-8952044 "AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex"
Reactome:R-HSA-8952618 "AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex"
Reactome:R-HSA-8952626 "AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex"
Reactome:R-HSA-8952631 "AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex"
Reactome:R-HSA-8952638 "AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex"
Reactome:R-HSA-8956025 "AcM-UBE2M transfers NEDD8 to CUL9:RBX1"