FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

modification-dependent protein catabolic process

ID (Ontology)

GO:0019941 (Gene Ontology)

Definition

The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein.

Also Known As

"modification-dependent protein breakdown" ; "modification-dependent protein catabolism" ; "modification-dependent protein degradation" (for all, see Synonyms field below)

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
modification-dependent protein catabolic process (all annotations which use CV term, excluding "NOT" statements)
involved_in \| modification-dependent protein catabolic process

Spanning Tree (Parents/Children)

macromolecule catabolic process
 |__protein catabolic process_______________________________
 |__modification-dependent macromolecule catabolic process__|
protein metabolic process                                   |
 |__protein catabolic process_______________________________|
                                                            modification-dependent protein catabolic process  376 rec.
                                                             |__oxidation-dependent protein catabolic process
                                                             |__prenylated protein catabolic process
                                                             |__ubiquitin-dependent protein catabolic process 369 rec.
                                                                 |__proteasome-mediated ubiquitin-dependent protein catabolic process(+) 285 rec.
                                                                 |__protein arginylation
                                                                 |__protein deubiquitination involved in ubiquitin-dependent protein catabolic process 1 rec.
                                                                 |__regulation of ubiquitin-dependent protein catabolic process(+) 74 rec.
                                                                 |__ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(+) 14 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	protein catabolic process modification-dependent macromolecule catabolic process
Part of
Synonyms & Secondary IDs
Synonyms
	"modification-dependent protein breakdown" EXACT "modification-dependent protein catabolism" EXACT "modification-dependent protein degradation" EXACT "modification-dependent proteolysis" EXACT "modification-initiated protein catabolic process" EXACT "modification-initiated protein catabolism" EXACT "modification-initiated proteolysis" EXACT "protein degradation tagging activity" RELATED "protein-ligand-dependent protein catabolic process" NARROW "protein-ligand-dependent protein catabolism" NARROW
Secondary IDs

External Crossreferences & Linkouts